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Invasive meningococcal disease (IMD) causes significant morbidity and mortality worldwide with serogroup B being the predominant serogroup in Australia and other countries for the past few decades. The licensed 4CMenB vaccine is effective in preventing meningococcal B disease. Emerging evidence suggests that although 4CMenB impact on carriage is limited, it may be effective against gonorrhoea due to genetic similarities between Neisseria meningitidis and Neisseria gonorrhoeae.
Citation: Reid A, Bowen AC, Brennan-Jones CG, Kuthubutheen JB. Congenital cytomegalovirus: the case for targeted infant screening in Australia. Med J
BCG vaccination modulates immune responses to unrelated pathogens. This off-target effect could reduce the impact of emerging pathogens. As a readily available, inexpensive intervention that has a well-established safety profile, BCG is a good candidate for protecting healthcare workers (HCWs) and other vulnerable groups against COVID-19.
Early 7vPCV schedules have limited impact on pneumococcal vaccine type carriage in PNG
Differences in pneumococcal serotypes, genotypes, and antimicrobial susceptibility between Aboriginal and non-Aboriginal children living in the same area
The prevalence of human rhinovirus (RV) species in children hospitalised with pneumonia in Manhiça, Mozambique
Pneumococcal surface protein A is immunogenic and natural anti-PspA immune responses are acquired through exposure and develop with age
RV-A and RV-C are endemic in South African children and HIV infection may be protective against RSV and bronchiolitis.
The benefits that swimming pools may bring to to ear and eye health in remote Aboriginal communities remains unresolved
The PneuCarriage project, a large, international multi-centre study for the identification of the best pneumococcal serotyping methods for carriage studies