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Research

Pulmonary delivery of cationic gold nanoparticles boost antigen-specific CD4+ T Cell Proliferation

Our findings demonstrate surface charge as a key parameter determining particle uptake by APC

Research

Management of invasive group A streptococcal infections

Invasive group A streptococcal disease in children includes deep soft tissue infection, bacteraemia, bacteraemic pneumonia, meningitis and osteomyelitis

Research

Adherence to secondary prophylaxis for rheumatic heart disease is underestimated by register data.

Adequate resources are needed for maintenance of data quality in acute rheumatic fever/ rheumatic heart disease registers to ensure provision of evidence-based care and accurate assessment of program impact.

Research

Randomised controlled trial of an iPad based early intervention for autism: TOBY playpad study protocol

This trial will determine the effectiveness of the TOBY App as a therapeutic complement to other early interventions children with ASD receive

Research

Recurrent MET fusion genes represent a drug target in pediatric glioblastoma

We identified previously unidentified gene fusions involving the MET oncogene in pediatric glioblastoma

Research

A fine balance and a shared learning journey: Exploring healthcare engagement through the experiences of youth with Neuromuscular Disorders

Explored Youth with Neuromuscular Disorders perceptions of health, health behaviors and healthcare engagement

Research

Immunodominant T-cell epitopes in the VP1 capsid protein of rhinovirus species A and C

Our results indicate a dissociation between the antibody and T-cell responses to rhinoviruses

Research

Secondary preventive medication use in a prevalent population-based cohort of acute coronary syndrome survivors

Longer time since last acute coronary syndrome admission was associated with dispensing fewer medications types and combinations in 2008

Research

Reduced transforming growth factor β1 (TGF-β1) in the repair of airway epithelial cells of children with asthma

Evidence into the role of TGF-β1 in airway epithelial repair in asthma is still controversial. This study tested the hypothesis that the reduced TGF-β1 levels previously observed in paediatric asthmatic airway epithelial cells directly contribute to the dysregulated repair seen in these cells.

Research

Epidural insertion height for ureteric reimplant surgery; does location matter?

The caudal catheter technique was superior at reducing pain interventions, particularly bladder spasm interventions