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New Home for ORIGINSThe Kids Joondalup will be the new home for the ORIGINS research and data teams
Research
Interferon regulatory factor 7 is a major hub connecting interferon-mediated responses in virus-induced asthma exacerbations in vivoThe objective of this study was to elucidate the molecular networks that underpin virus-induced exacerbations in asthmatic children in vivo.
Research
Ndrg1 in development and maintenance of the myelin sheathCMT4D disease is a severe autosomal recessive demyelinating neuropathy with extensive axonal loss leading to early disability, caused by mutations...
Research
Differences in innate immune function between allergic and nonallergic children: New insights into immune ontogenyWe sought to explore whether allergic children show differences in microbial Toll-like receptor (TLR)-mediated responses over their first 5 years of life.
Research
Diagnosis, Genetics, and Therapy of Short Stature in Children: A Growth Hormone Research Society International PerspectiveThe Growth Hormone Research Society (GRS) convened a Workshop in March 2019 to evaluate the diagnosis and therapy of short stature in children
Research
QuantSeq. 3′ Sequencing combined with Salmon provides a fast, reliable approach for high throughput RNA expression analysisQuantSeq, coupled with a fast quantification method such as Salmon, should provide a viable alternative to traditional RNA-Seq in many applications
We described the occurrence of scoliosis in Rett syndrome, how it develops and how it is influenced by the individual's age, mutation type, and walking ability.
Research
Soft neurological signs and prenatal alcohol exposure: A population-based study in remote AustraliaSoft neurological signs were more common in children with prenatal alcohol exposure or FASD, consistent with the known neurotoxic effect of PAE
Research
Application of a marginal structural model and simulation of a cash transfer programmeParental investments in children are an important determinant of human capability formation.
Research
Clinical cardiovascular risk during young adulthood in offspring of hypertensive pregnancies:Offspring of hypertensive pregnancies have increased cardiovascular risk factors during childhood.