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Research

Reduced transforming growth factor β1 (TGF-β1) in the repair of airway epithelial cells of children with asthma

Evidence into the role of TGF-β1 in airway epithelial repair in asthma is still controversial. This study tested the hypothesis that the reduced TGF-β1 levels previously observed in paediatric asthmatic airway epithelial cells directly contribute to the dysregulated repair seen in these cells.

Research

Epidural insertion height for ureteric reimplant surgery; does location matter?

The caudal catheter technique was superior at reducing pain interventions, particularly bladder spasm interventions

Research

Sole-parent work schedules and adolescent wellbeing: Evidence from Australia

Explores the effects of parental work schedules on the mental and physical health of adolescents aged 15-20 in sole-parent families

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A longitudinal study of natural antibody development to pneumococcal surface protein A families 1 and 2 in Papua New Guinean Highland children: a cohort study

Pneumococcal surface protein A is immunogenic and natural anti-PspA immune responses are acquired through exposure and develop with age

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How can clinical ethics guide the management of comorbidities in the child with Rett syndrome?

This paper reviews the disorder Rett syndrome and evidence for the management of scoliosis and poor growth within a clinical ethics framework

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A prospective investigation of dietary patterns and internalizing and externalizing mental health problems in adolescents

Our findings only lend partial support to a link between diet and mental health, specific to females consuming a Western diet and to externalizing behaviours

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Early life events and motor development in childhood and adolescence: A longitudinal study

Antenatal, perinatal and neonatal factors affecting motor development from late childhood to adolescence were explored.

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Increasing incidence of type 2 diabetes in Indigenous and non-Indigenous children in Western Australia, 1990-2012

In this study, we aimed to determine the incidence and incidence rate trends of childhood T2D in Indigenous and non-Indigenous children in WA.

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New South Wales child development study (NSW-CDS): An Australian multiagency, multigenerational, longitudinal record linkage study

Identify risk and protective factors for later childhood-onset and adolescent-onset mental health problems, and other adverse social outcomes

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Further examination of the reducing transition rate in ultra high risk for psychosis samples: The possible role of earlier intervention

The rate of transition to psychotic disorder in ultra high risk (UHR) patients has declined in recent cohorts. The reasons for this are unclear, but may...