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Research
Phage cocktail amikacin combination as a potential therapy for bacteremia associated with carbapenemase producing colistin resistant Klebsiella pneumoniaeThe increasing occurrence of hospital-associated infections, particularly bacteremia, caused by extensively drug-resistant (XDR) carbapenemase-producing colistin-resistant Klebsiella pneumoniae highlights a critical requirement to discover new therapeutic alternatives. Bacteriophages having host-specific bacteriolytic effects are promising alternatives for combating these pathogens.
Research
Following in Banting’s footsteps or straying from the path? Observations from contemporary diabetes innovationWhile advancements in the treatment of diabetes continue to rapidly evolve, many of the newer technologies have financial barriers to care, opposing the egalitarian ethos of Banting who sold his patent on insulin for a nominal cost to allow it to be made widely available. Inequity in access to new therapies drives disparity in diabetes burden with potential for these gaps to widen in the future.
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New Home for ORIGINSThe Kids Joondalup will be the new home for the ORIGINS research and data teams
Research
Ndrg1 in development and maintenance of the myelin sheathCMT4D disease is a severe autosomal recessive demyelinating neuropathy with extensive axonal loss leading to early disability, caused by mutations...
Research
Differences in innate immune function between allergic and nonallergic children: New insights into immune ontogenyWe sought to explore whether allergic children show differences in microbial Toll-like receptor (TLR)-mediated responses over their first 5 years of life.
Research
Maternity-care: measuring women’s perceptionsDevelopment of an instrument to assess women's perception of their entire maternity-care experience
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Soft neurological signs and prenatal alcohol exposure: A population-based study in remote AustraliaSoft neurological signs were more common in children with prenatal alcohol exposure or FASD, consistent with the known neurotoxic effect of PAE
Research
The relationship between school climate and mental and emotional wellbeing over the transition from primary to secondary schoolThe current study examined the relationship between students’ mental and emotional wellbeing and factors pertaining to school climate, focusing on the...
Research
Clinical cardiovascular risk during young adulthood in offspring of hypertensive pregnancies:Offspring of hypertensive pregnancies have increased cardiovascular risk factors during childhood.
Research
PRAGMA-CF. A Quantitative Structural Lung Disease Computed Tomography Outcome in Young Children with Cystic FibrosisChest computed tomography (CT) is the gold standard for demonstrating cystic fibrosis (CF) airway disease. However, there are no standardized outcome...