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Showing results for "Neuromuscular disorders "
It is plausible that offspring born to mothers using tobacco during pregnancy may have increased risk of mood disorders (depression and bipolar disorders); however, mixed results have been reported.
Despite the teratogenic effects of alcohol, little is known about the safety of pharmacotherapies such as acamprosate for the treatment of alcohol use disorders in pregnancy. The aims of this study were to investigate, in a mouse model, the effects of maternally administered acamprosate on maternal and neonatal health, offspring neurodevelopment and behaviour, as well as examine whether acamprosate reduces the neurological harm associated with alcohol consumption in pregnancy.
It is well recognized that genetic disease makes a significant contribution to childhood illness. Here, we present recent population data describing...
To assess the association between in utero exposure to seasonal inactivated influenza vaccine (IIV) and the risk of a diagnosis of a neurodevelopmental disorder in early childhood.
This study investigated the capacity of three accelerometer-type devices to measure walking activity in Rett syndrome
Eating disorder prevalence rates were significantly greater when using DSM-5 than DSM- IV-TR criteria, at all time points for females and at age 17 only...
Purging at age 17 and externalising behaviour problems at age 14 were the strongest predictors of eating disorder persistence to age 20.
This research explored the relationship between the broader autism phenotype (BAP) among parents, an index of genetic liability for ASD, and proband...
Evidence about the association between maternal mental health disorders and stillbirth and infant mortality is limited and conflicting. We aimed to examine whether maternal prenatal mental health disorders are associated with stillbirth and/or infant mortality. MEDLINE, Embase, PsycINFO, and Scopus were searched for studies examining the association of any maternal prenatal (occurring before or during pregnancy) mental health disorder(s) and stillbirth or infant mortality. A random-effects meta-analysis was used to calculate pooled odds ratios (ORs) with 95% confidence intervals (CIs). The between-study heterogeneity was quantified using the I2 statistic. Subgroup analyses were performed to identify the source of heterogeneity.
This chapter discusses the importance of investment in early life determinants of health to break the cycle of long-term disadvantage. This chapter addresses these issues while focussing on neurodevelopmental disorders and their related mental health concerns as the targets at the centre of a biopsychosocial transformation of the health system.