A hallmark of atopic asthma is development of chronic airways hyper-responsiveness (AHR) that persists in the face of ongoing exposure to perennial...
The authors previously reported an increased risk of hospitalisation for acute lower respiratory infection up to age 2 years in children delivered by…
The aim of this study was to explore associations between severe respiratory infections and atopy in early childhood with persisting wheeze and asthm…
We aimed to measure the antibody development to 2 bacteria in a birth cohort at high risk of allergic disease, and to assess which responses are asth…
Information is accumulating which implicates airway inflammation resulting from respiratory viral infections, acting against a background of atopy.
We compared neonatal T reg from children born in western conditions (Australia) with those of neonates born in high microbial conditions (Papua New G…
Suggests that IL-1R1 expression provides an additional level of Myd88-dependent signaling during this period of heighted susceptibility to infection.
The aim of this study was to examine the relationship between nasopharyngeal pneumococcal colonization in early life and the development of T cell re…
The objective was to determine the association between maternal serum 25(OH)-vitamin D concentrations and behavioural, emotional and language outcome…
To show underlying mechanisms, we examined differences in T-cell gene expression in samples at birth and at 1 year in children with and without IgE a…