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In the longest reported follow-up of infants who received aP vaccine at birth, we found a trend to lower PT IgG antibodies post booster compared with receipt...
Population-based birth cohorts on asthma and allergies increasingly provide new insights into the development and natural history of the diseases.
Pregnancy is a time of vulnerability for vitamin D insufficiency, and there is an emerging literature associating low levels of 25(OH)-vitamin D with...
Concerns about the risk of inducing immune deviation-associated "neonatal tolerance" as described in mice have restricted the widespread adoption...
The effect of breast-feeding on the development of allergic disease is uncertain
Atopic asthma is the most common form of asthma, particularly during childhood, and in many cases it persists into adult life.
Interleukin-10 is a key immunomodulatory cytokine the principal function of which is to limit the magnitude of immune response.
Childhood asthma is a condition characterized by airflow obstruction that varies in time spontaneously, in response to various environmental stimuli...
The hallmark of atopic asthma is transient airways hyperresponsiveness (AHR) preceded by aeroallergen-induced Th-cell activation.
Elucidation of early life factors is critical to understand the development of allergic diseases, especially those manifesting in early life such as food allerg