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Research
Acute Lymphoblastic Leukemia in Infants: A Distinctive, High-Risk Subtype of Childhood Acute Lymphoblastic LeukemiaAcute lymphoblastic leukemia (ALL) in infants younger than 1 year of age is an aggressive, high-risk subtype of childhood ALL. Infant ALL with KMT2A-r is characteristically poorly responsive to chemotherapy and hematopoietic stem cell transplantation. New strategies, such as molecularly targeted therapies and immunotherapies, are in development and show promise in preclinical models and early phase studies.
Research
Maternal consumption of coffee and tea during pregnancy and risk of childhood ALL: a pooled analysis from the childhood Leukemia International ConsortiumOur findings suggest that high coffee intake during pregnancy may increase risk of childhood acute lymphoblastic leukemia
Research
Cost-effectiveness analysis of routine screening using massively parallel sequencing for maturity-onset diabetes of the young in a pediatric diabetes cohortRoutine MPS screening for Maturity-onset diabetes of the young in the pediatric population with diabetes could reduce health system costs and improve patient QoL
Research
Genome-wide association study of autistic-like traits in a general population study of young adultsResearch has proposed that autistic-like traits in the general population lie on a continuum, with clinical ASD representing the extreme end of this...
Research
Long-term survival for infants born with orofacial clefts in Western AustraliaParents with a child diagnosed with an OFC ± additional minor anomalies only can be reassured that the OFC does not influence survival rates in infancy
Research
Dynamic molecular changes during the first week of human life follow a robust developmental trajectorySystems biology and innovative data integration can provide fresh insights into the molecular ontogeny of the first week of life
Research
Identification and genetic determination of an early life risk disposition for depressive disorder:Progress in psychiatric genetics has been slow despite evidence of high heritability for most mental disorders
Embrace the potential of children with Rett Syndrome by exploring how to plan opportunities for uptime, maximizing their engagement and participation in meaningful activities.
News & Events
Introducing the Rio Tinto Children's Diabetes Centre, A JDRF Global Centre of ExcellenceIntroducing the Rio Tinto Children's Diabetes Centre: A JDRF Global Centre of Excellence
News & Events
Montanna's diabetes dashA diabetes diagnosis is a shock at any time but spare a thought for the Rustens who jumped on a plane to Perth from Kununurra within an hour of diagnosis.