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Research

Safety and Tolerability of V114 Pneumococcal Vaccine in Infants: A Phase 3 Study

Disease caused by Streptococcus pneumoniae is associated with considerable morbidity and mortality in children. Pneumococcal conjugate vaccines are well tolerated and effective at reducing pneumococcal disease caused by vaccine serotypes. VAXNEUVANCE (V114) is a 15-valent PCV containing 13 serotypes in Prevnar 13, plus serotypes 22F and 33F. This large phase 3 study evaluated safety and tolerability of V114 in infants. 

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Longitudinal Cognitive Performance in Individuals at Ultrahigh Risk for Psychosis: A 10-year Follow-up

The onset of psychosis was not associated with deterioration in cognitive ability

Research

Women Migrants in Western Australia: Case Studies of Resilience and Empowerment

We propose that women migrants, through alliances and collaboration, cross borders of learning and work towards generating change and transformation

Research

Machine learning and clinical epigenetics: a review of challenges for diagnosis and classification

We now have a growing number of epigenetic alterations in disease, and this offers a chance to increase sensitivity and specificity of future diagnostics and therapies

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High prevalence of mgrB-mediated colistin resistance among carbapenem-resistant Klebsiella pneumoniae is associated with biofilm formation, and can be overcome by colistin-EDTA combination therapy

The global prevalence of colistin-resistant Klebsiella pneumoniae (ColRkp) facilitated by chromosomal and plasmid-mediated Ara4N or PEtN-remodeled LPS alterations has steadily increased with increased colistin usage for treating carbapenem-resistant K. pneumoniae (CRkp).

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Behavior in Children with Fetal Alcohol Spectrum Disorders in Remote Australia: A Population-Based Study

Children with FASD have more teacher-reported behavioral impairment than children without FASD. In remote Australian communities, academic performance is poor.

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The influence of infant feeding attitudes on breastfeeding duration: evidence from a cohort study in rural Western Australia

The Rural Infant Feeding Study aimed to describe the factors associated with breastfeeding practice from birth to 12 months of age in rural Western Australia.

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The Impact of Maternal Gestational Stress on Motor Development in Late Childhood and Adolescence: A Longitudinal Study

Stressful events experienced in late pregnancy were negatively related with offspring motor development

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A time series analysis of alcohol-related presentations to emergency departments in Queensland following the increase in alcopops tax

The increase in tax on ‘alcopops’ did not result in any reduction in alcohol-related harms in this population

Research

Regulatory role of IL10 genetic variations in determining allergen-induced TH2 cytokine responses in children

Interleukin-10 is a key immunomodulatory cytokine the principal function of which is to limit the magnitude of immune response.