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A Phase 3, Randomized, Double-Blind, Comparator-Controlled Study to Evaluate Safety, Tolerability, and Immunogenicity of V114, a 15-Valent Pneumococcal Conjugate Vaccine, in Allogeneic Hematopoietic Cell Transplant Recipients (PNEU-STEM)

Individuals who receive allogeneic hematopoietic cell transplant (allo-HCT) are immunocompromised and at high risk of pneumococcal infections, especially in the months following transplant. This study evaluated the safety and immunogenicity of V114 (VAXNEUVANCE; Merck, Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, NJ, USA), a 15-valent pneumococcal conjugate vaccine (PCV), when given to allo-HCT recipients. 

ISPAD Clinical Practice Consensus Guidelines 2022: Exercise in children and adolescents with diabetes

Liz Davis MBBS FRACP PhD Co-director of Children’s Diabetes Centre Co-director of Children’s Diabetes Centre Professor Davis is a paediatric

NMR Spectroscopy-Based Lipoprotein and Glycoprotein Biomarkers Differentiate Acute and Chronic Inflammation in Diverse Healthy and Disease Population Cohorts

Understanding the distribution and variation in NMR-based inflammatory markers is crucial to the evaluation of their clinical utility in disease prognosis and diagnosis. We applied high-resolution 1H NMR spectroscopy of blood plasma and serum to measure the acute phase reactive glycoprotein signals  and the subregions of the lipoprotein-based Supramolecular Phospholipid Composite signals in a large multicohort population study.

Bullying behaviour following students’ transition to a secondary boarding school context

This study investigated the prevalence and types of bullying behaviour that boarding students experienced during the transition to a secondary boarding school.

Factors associated with trajectories of psychological distress for Australian fathers across the early parenting period

Early postnatal factors associated with fathers' persistent distress were identified, providing opportunities for early identification and targeted early...

How Does Support From Peers Compare With Support From Adults as Students Transition to Secondary School?

Students who expect and experience a positive transition to secondary school are generally well-supported by their peers, school, and family.

Vitamin D deficiency and the lung: Disease initiator or disease modifier?

Vitamin D deficiency is a global public health problem and has been associated with an increased incidence and severity of many diseases including diseases...

An eleven-year evaluation of the effect of community treatment orders on changes in mental health service use

Many studies of compulsory community treatment have assessed their effect early on after the implementation of legislation.

Genetic variants in ER cofactor genes and endometrial cancer risk

Given that the transcriptional regulatory activity of estrogen receptor (ER) is modulated by its biochemical cofactors, genetic variation within the ER...

The dual-pathway and cognitive-behavioural models of binge eating: prospective evaluation and comparison

The aim of this study was to evaluate and compare the dual-pathway, original cognitive-behavioural, and enhanced "transdiagnostic" cognitive-behavioural...