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Study protocol of a multicentre, randomised, controlled trial evaluating the effectiveness of probiotic and peanut oral immunotherapyPeanut allergy is the the most common cause of life-threatening food-induced anaphylaxis. There is currently no effective long-term treatment. There is a pressing need for definitive treatments that improve the quality of life and prevent fatalities. Allergen oral immunotherapy (OIT) is a promising approach, which is effective at inducing desensitisation; however, OIT has a limited ability to induce sustained unresponsiveness (SU).
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Childhood obesity: what we have learnt from our failure to engage mothers in our interventionWith more than one in four Australian children overweight or obese, and the significant risks this poses for health problems like asthma, depression,...
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Probiotics for treatment and primary prevention of allergic diseases and asthma: looking back and moving forwardReview treatment and primary prevention studies, recent meta-analyses, and discuss the current understanding of the role of probiotics in this context
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Nutritional approaches for the primary prevention of allergic disease: An updateThe dramatic rise in early childhood allergic diseases indicates the specific vulnerability of the immune system to early life environmental changes.
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Respiratory allergen from house dust mite is present in human milk and primes for allergic sensitization in a mouse model of asthmaThese data highlight that antigen administration to the neonate through the oral route may contribute to child allergic sensitization and have important...
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Examining subfertility and its treatment in a population-based cohort of pregnant womenInvestigators: Nicole Burger Assisted reproductive technologies have been associated with adverse perinatal outcomes, however subfertile women who
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The Cardiovascular Risk Evaluation in Expectant Fathers (CARE-Dads) StudySusan Prescott MBBS BMedSci PhD FRACP Honorary Research Fellow susan.prescott@thekids.org.au Honorary Research Fellow Susan Prescott is a Professor
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Feasibility of home-based urine collection in children under 5 years in the ORIGINS birth cohort study: mixed method protocol and sample completion resultsUrine is an attractive biospecimen for nutritional status and population health surveys. It is an excellent non-invasive alternative to blood for appropriate biomarkers in young children and is suitable for home-based collection, enabling representative collections across a population. However, the bulk of literature in this population is restricted to collection in primary care settings.
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“Stop, pause and take a break”: a mixed methods study of the longer-term outcomes of digital emotional wellbeing training for perinatal womenMaternal psychological distress is related to poorer physical and mental health as well as child developmental problems. Interventions that optimise maternal mental health and wellbeing during the "first 1,000 days" of life should have wide-reaching benefits for the mother and her child.
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The ORIGINS Project: A Cross-Sectional Analysis of the Nutrition Profile of Pregnant Women in a Longitudinal Birth CohortPregnancy is an opportunistic time for dietary intake to influence future disease susceptibility in offspring later in life. The ORIGINS Project was established to identify the factors that contribute to 'a healthy start to life' through a focus supporting childhood health and preventing disease (including non-communicable diseases).