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Asparaginase is a critical component of modern multi-agent chemotherapy regimens for paediatric acute lymphoblastic leukaemia and lymphoblastic lymphoma, with inadequate exposure leading to inferior patient outcomes.
Australia introduced a hybrid Respiratory Syncytial Virus (RSV) Maternal and Infant Protection Program (RSV-MIPP) in 2025, using National Immunisation Program-funded RSV vaccine for pregnant people from 28 weeks' gestation and jurisdiction-funded nirsevimab. We estimated real-world effectiveness and assessed the impact of the RSV-MIPP program across a participating surveillance network.
To identify factors influencing implementation and integration of the paediatric ESCALATION system in country Western Australia.
The Bayley Scales of Infant and Toddler Development are widely used to assess early development, yet evidence for inter-rater reliability in multidisciplinary contexts remains limited. This study evaluated inter-rater reliability and agreement of the newest edition, Bayley-4, at age two years when administered by a multidisciplinary allied health team within a longitudinal cohort.
This study aimed to investigate the associations between glycemic outcomes and a range of clinical and demographic factors, including treatment modality, sex, age, diabetes duration, and body mass index, in youth with type 1 diabetes in an international registry.
Mouse models are widely used to study heat-related physiological responses as they provide insights relevant to human health. However, species differences (including nocturnal behavior) and standard housing below the thermoneutral zone (TNZ; 26°C-34°C) can confound comparisons. This systematic review evaluates methodologies, including housing temperatures, used in mouse heat-exposure studies published over the past 4 years.
Deliberate exposure to ionizing radiation during medical investigations, such as chest CT, should be as low as reasonably practicable to reduce the risk of inducing cancer. Certain populations are at particular risk, such as those undergoing lung cancer screening and workers exposed to dust, and require multiple scans over time with high baseline risk.
This study examines whether nonstandard work schedules (NSWS) improve or hinder work-life balance (WLB) for parents and non-parents in dual-earner households.
On this Research Impact page, we list stories helping to show our exciting in-progress research currently "in the pipeline" towards translation. This is research which shows a real spark of potential to make a significant difference to children and families worldwide.
Middle ear infections are one of the main reasons that children visit a GP, are prescribed antibiotics and need surgery. Aboriginal children are particularly susceptible and commonly suffer from hearing loss which can affect speech and learning.