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Research
A comparison of major trauma patient transport destination in metropolitan Perth, Western AustraliaThis study examines the characteristics and outcomes of major trauma patients between transport destinations
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"This is my boy's health! Talk straight to me!" perspectives on accessible and culturally safe care among Aboriginal and Torres Strait Islander patients of clinical genetics servicesAboriginal and Torres Strait Islander people do not enjoy equal access to specialist health services that adequately meet their needs. Clinical genetics services are at the vanguard of realising the health benefits of genomic medicine. As the field continues to expand in clinical utility and implementation, it is critical that Aboriginal and Torres Strait Islander people are able to participate and benefit equally to avoid further widening of the existing health gap. This is the first study to explore barriers to accessing clinical genetics services among Aboriginal and Torres Strait Islander people, which has been acknowledged as a key strategic priority in Australian genomic health policy.
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Associations of serum short-chain fatty acids with circulating immune cells and serum biomarkers in patients with multiple sclerosisAltered composition of gut bacteria and changes to the production of their bioactive metabolites, the short-chain fatty acids (SCFAs), have been implicated in the development of multiple sclerosis (MS). However, the immunomodulatory actions of SCFAs and intermediaries in their ability to influence MS pathogenesis are uncertain. In this study, levels of serum SCFAs were correlated with immune cell abundance and phenotype as well as with other relevant serum factors in blood samples taken at first presentation of Clinically Isolated Syndrome (CIS; an early form of MS) or MS and compared to healthy controls. There was a small but significant reduction in propionate levels in the serum of patients with CIS or MS compared with healthy controls.
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Integrated analyses of zebrafish miRNA and mRNA expression profiles identify miR-29b and miR-223 as potential regulators of optic nerve regenerationZebrafish have the ability to regenerate damaged parts of their central nervous system (CNS) and regain functionality of the affected area.
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Protocol for the Care-IS Trial: a randomised controlled trial of a supportive educational intervention for carers of patients with high-grade glioma (HGG).This paper outlines the objectives of a randomised control trial that will be conducted to investigate primary carers of those with high-grade glioma.
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Rapid recruitment of CD14+ monocytes in experimentally induced allergic rhinitis in human subjectsMononuclear phagocyte population is directly involved in the production of proinflammatory chemokines that attract other immune cells
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Development of a human papillomavirus vaccination intervention for Australian adolescentsIntervention to address young people's low levels of understanding, to promote their involvement in consent and reduce vaccination-related fear and anxiety.
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If it’s about me, why do it without me? Genuine student engagement in school cyberbullying educationThis study reports on a three-year group randomized controlled trial, the Cyber Friendly Schools Project (CFSP), aimed to reduce cyberbullying among grade 8...
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Prevention of neural tube defects with folateA programme of monitoring mandatory fortification has been established in Australia.
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Early diet quality in a longitudinal study of Australian children: Associations with nutrition and body mass index later in childhood and adolescenceThe aims of this study were to determine whether early childhood dietary quality was associated with infant and adolescent nutrition, and body mass index.