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The aim of the Computational Biology team is to understand how individual bases in our genome predispose, alter and interact in normal and disease contexts.
Research
Genome-wide association meta-analysis of single-nucleotide polymorphisms and symptomatic venous thromboembolism during therapy for ALL and lymphoma in caucasian childrenThe largest GWAS meta-analysis conducted to date associating SNPs to venous thromboembolism in children and adolescents treated on childhood ALL protocols
Research
Evidence of a reduction over time in the behavioral severity of autistic disorder diagnosesWe examined whether there were changes over time in the qualitative and quantitative phenotype of individuals who received the diagnosis of Autistic Disorder.
Research
Evaluation of the Learning+ Pilot ProgramYasmin Adrienne Harman-Smith Gregory BA, BHlthSc(Hons), PhD BSocSci, MPhil Head, Early Years Systems Evidence; Head, Tenders Support Unit Project
News & Events
Diabetes researcher Dr Aveni Haynes awarded prestigious international fellowshipCongratulations to Principal Research Fellow Dr Aveni Haynes from The Kids Research Institute Australia and the University of Western Australia.
News & Events
Hybrid Closed Loop insulin delivery system has potential to restore hypoglycaemia awarenessShort term use of a hybrid closed loop system might preferentially benefit people with type 1 diabetes who have impaired awareness of hypoglycaemia (IAH), according to new research from the Children's Diabetes Centre.
Tourette syndrome is a neurodevelopmental disorder characterised by uncontrollable movements and vocalisations known as tics.
Research
Increasing airway obstruction through life following bronchopulmonary dysplasia: a meta-analysisFew studies exist investigating lung function trajectories of those born preterm; however growing evidence suggests some individuals experience increasing airway obstruction throughout life. Here we use the studies identified in a recent systematic review to provide the first meta-analysis investigating the impact of preterm birth on airway obstruction measured by the forced expiratory volume in 1 s (FEV1) to forced vital capacity (FVC) ratio.
Research
Feasibility of upper airway collapsibility measurements in anesthetized childrenPatients with a propensity for upper airway obstruction, including those with obstructive sleep apnea (OSA), are vulnerable in the perioperative period. OSA is an increasingly common disorder in children and, when present, is associated with an increased risk of perioperative respiratory adverse events (PRAE),1 morbidity, and mortality. Therefore, identifying at-risk patients is vital to provide tailored perioperative anesthetic management.
Research
Reporting Both Unadjusted and Adjusted Estimates Is Essential to the Interpretation of Randomized Clinical Trial Results - ReplyAndrew Matt Videos Whitehouse Watch and listen to Andrew Cooper PhD BCA Marketing, BSc Statistics and Applied Statistics, PhD Deputy Director (