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Research

Global molecular diversity of RSV – the “INFORM RSV” study

Respiratory syncytial virus (RSV) is a global cause of severe respiratory morbidity and mortality in infants. While preventive and therapeutic interventions are being developed, including antivirals, vaccines and monoclonal antibodies, little is known about the global molecular epidemiology of RSV. INFORM is a prospective, multicenter, global clinical study performed by ReSViNET to investigate the worldwide molecular diversity of RSV isolates collected from children less than 5 years of age.

Research

Spatial analysis of hepatobiliary abnormalities in a population at high-risk of cholangiocarcinoma in Thailand

Cholangiocarcinoma (CCA) is a serious health challenge with low survival prognosis. The liver fluke, Opisthorchis viverrini, plays a role in the aetiology of CCA, through hepatobiliary abnormalities: liver mass (LM), bile duct dilation, and periductal fibrosis (PDF). A population-based CCA screening program, the Cholangiocarcinoma Screening and Care Program, operates in Northeast Thailand. Hepatobiliary abnormalities were identified through ultrasonography.

Research

Oxidative stress and abnormal bioactive lipids in early cystic fibrosis lung disease

Several lipid biomarkers of early cystic fibrosis lung disease were identified, which point toward potential disease monitoring and therapeutic approaches

Research

Risks and obstacles in implementing a public health approach to the wellbeing and protection of children

We have also been engaged with and excited by the attempts to adopt a public health approach to the care and protection of children as described throughout this book

Research

Cohort profile: Pregnancy and childhood epigenetics (PACE) consortium

The PACE Consortium represents the first steps in the discovery of the role of DNA methylation in health and disease

Research

A comparison of activity, participation and quality of life in children with and without spastic diplegia cerebral palsyNew Page

The aim of this study wa to measure activity, participation and QoL in children with CP and to determine how these differ from a comparable group of...

Research

Psychosocial moderators of associations between life events and changes in physical activity after leaving high school

This study examines the associations between life events & changes in leisure-time physical activity after leaving high school in young people from rural...

Research

Der p 11 is a major allergen for house dust mite-allergic patients suffering from atopic dermatitis

House dust mites (HDMs) belong to the most potent indoor allergen sources worldwide and are associated with allergic manifestations in the respiratory tract.

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A whole-of-population study of term and post-term gestational age at birth and children's development

Relative risks of developmental vulnerability for each week of gestation were calculated with adjustment for confounders and addressing missing information.