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Research
Responsiveness of the human airway in vitro during deep inspiration and tidal oscillationThe aim of this study was to examine the in vitro response of isolated human airways to the dynamic mechanical stretch associated with normal breathing.
Research
Elemental carbon exposure and lung function in schoolchildren from Mexico CityThough exposure to air pollution has a detrimental effect on respiratory health, few studies have examined the association between elemental carbon exposure...
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Applying causal inference and Bayesian statistics to understanding vaccine safety signals using a simulation studyCommunity perception of vaccine safety influences vaccine uptake. Our objective was to assess current vaccine safety monitoring by examining factors that may influence the availability of post-vaccination survey data, and thereby the specificity and sensitivity of existing signal detection methods.
Research
Phage therapy could be key to conquering persistent bacterial lung infections in childrenPersistent bacterial lung infections in children lead to significant morbidity and mortality due to antibiotic resistance. In this paper, we describe how phage therapy has shown remarkable efficacy in preclinical and clinical studies, demonstrating significant therapeutic benefits through various administration routes.
Research
Economic burden of multidrug-resistant tuberculosis on patients and households: a global systematic review and meta-analysisMultidrug-resistant tuberculosis (MDR-TB) is a major health threat worldwide, causing a significant economic burden to patients and their families. Due to the longer duration of treatment and expensive second-line medicine, the economic burden of MDR-TB is assumed to be higher than drug-susceptible TB.
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Updating estimates of Plasmodium knowlesi malaria risk in response to changing land use patterns across Southeast AsiaPlasmodium knowlesi is a zoonotic parasite that causes malaria in humans. The pathogen has a natural host reservoir in certain macaque species and is transmitted to humans via mosquitoes of the Anopheles Leucosphyrus Group. The risk of human P. knowlesi infection varies across Southeast Asia and is dependent upon environmental factors.
News & Events
Supporting Families ProjectProudly funded by a Telethon Trust Research Grant, the Supporting Families project started in 2024 with the aim of co-designing a new clinical pathway for children with early stage type 1 diabetes (T1D).
Research
Rationale and methods of a randomized controlled trial of immunogenicity, safety and impact on carriage of pneumococcal conjugate and polysaccharide vaccines in infants in Papua New GuineaVaccination trials in high endemicity areas are needed to provide evidence and guidance on idea strategies to protect children in these areas against infections
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Development and Validation of a Multifactor Mindfulness Scale in Youth: The Comprehensive Inventory of Mindfulness Experiences-Adolescents (CHIME-A)This study aimed to investigate whether multifactor scales of mindfulness can be used in adolescents.
Research
Cohort profile: Pregnancy and childhood epigenetics (PACE) consortiumThe PACE Consortium represents the first steps in the discovery of the role of DNA methylation in health and disease