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News & Events
West Australian Empowering Innovation seriesThe Kids Research Institute Australia is proud to feature our commercial spin-off company, Phylogica, in the West Australian's Empowering Innovation series.
Research
Fetal androgen exposure and pragmatic language ability of girls in middle childhoodPrenatal exposure to testosterone has been shown to affect fetal brain maturation as well as postnatal cognition and behavior in animal studies.
News & Events
Vaccination seminar presentationsOn Monday May 30, The Kids Research Institute Australia held a free public seminar on vaccination, hearing from paediatricians and infectious disease researchers.
Research
Paediatric Medicinal Formulation Development: Utilising Human Taste Panels and Incorporating Their Data into Machine Learning TrainingThis review paper explores the role of human taste panels and artificial neural networks (ANNs) in taste-masking paediatric drug formulations. Given the ethical, practical, and regulatory challenges of employing children, young adults (18-40) can serve as suitable substitutes due to the similarity in their taste sensitivity. Taste panellists need not be experts in sensory evaluation so long as a reference product is used during evaluation; however, they should be screened for bitterness taste detection thresholds.
Research
Taste-Masked Flucloxacillin Powder Part 1: Optimisation of Fabrication Process Using a Mixture Design ApproachIt is extremely challenging to formulate age-appropriate flucloxacillin medicines for young children, because flucloxacillin sodium (FS) has a lingering, highly bitter taste, dissolves quickly in saliva, and requires multiple daily dosing at relatively large doses for treating skin infections. In this paper, we describe a promising taste-masked flucloxacillin ternary microparticle (FTM) formulation comprising FS, Eudragit EPO (EE), and palmitic acid.
Research
Cyber-Friendly SchoolsThis chapter describes a whole-school cyberbullying intervention developed and evaluated in Western Australia with secondary school students aged 13–18 years old
Research
Relevance of Aboriginal Peer-Led Parent Support: Strengthening the Child Environment in Remote AreasThis research highlights the critical emerging role of peer support workers in home visiting family support in a remote area of Australia
Research
Environment Changes Genetic Effects on Respiratory Conditions and Allergic PhenotypesGenotype-phenotype associations relating to bronchitis and allergy susceptibility are dependent on the environment
Research
Meningococcal serogroup B-specific responses after vaccination with bivalent rLP2086Assessment of the persistence of bactericidal antibodies up to 4 years after a three-dose schedule of bivalent rLP2086
News & Events
Hopscotch 7th April 2022: The next generation of cancer treatmentsOur first Hopscotch event of 2022 explored exciting new frontiers of cancer treatments happening in the WA Kids Cancer Centre.