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Rhinovirus-induced asthma exacerbations and risk populationsAsthma exacerbations are heterogeneous conditions that involve the complex interplay between environmental exposures and innate and adaptive immune function
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After asthma: Redefining airways diseasesIdentify entrenched areas of asthma management and treatment in which progress has stalled and to challenge current principles
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Prophylactic use of sublingual allergen immunotherapy in high-risk children: A pilot studyThese findings suggest that this modified version of SLIT should be considered for retesting of mucosal-based immunotherapy for atopic asthma prevention.
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Prenatal adverse life events increase the risk for atopic diseases in children, which is enhanced in the absence of a maternal atopic predispositionThere is evidence to suggest an association between prenatal maternal stress and the development of asthma or other atopic diseases in offspring.
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High fractional exhaled nitric oxide and sputum eosinophils are associated with an increased risk of future virus-induced exacerbations: A prospective cohort study.High fractional exhaled nitric oxide and sputum eosinophils are associated with an increased risk of future virus-induced exacerbations.
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Severity and persistence of asthma and mental health: a birth cohort studyThe goal of the current study was to investigate asthma and mental health among youth in the community.
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Vitamin D 3 deficiency enhances allergen-induced lymphocyte responses in a mouse model of allergic airway diseaseIn this study, using a mouse model, we determined whether vitamin D deficiency in utero and during early life modulated the severity of asthma.
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Regulatory role of IL10 genetic variations in determining allergen-induced TH2 cytokine responses in childrenInterleukin-10 is a key immunomodulatory cytokine the principal function of which is to limit the magnitude of immune response.
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Viral infections and atopy in asthma pathogenesis: New rationales for asthma prevention and treatmentProspective birth cohort studies tracking asthma initiation and consolidation in community cohorts have identified viral infections occurring against a...
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UV exposure and protection against allergic airways diseaseAsthma is a chronic inflammatory disease of the small and large conducting airway mucosa characterised by Th2 cell immunity.