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Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotypePrevious analyses of family data from the Tasmanian Longitudinal Health Study provide evidence that this phenotype has a stronger genetic cause than asthma...
Research
Hierarchy and molecular properties of house dust mite allergensThe allergenic load of house dust mite allergy is largely constituted by a few proteins with a hierarchical pattern of allergenicity.
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A health inequality analysis of childhood asthma prevalence in urban AustraliaLong-standing health inequalities in Australian society that were exposed by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic were described as "fault lines" in a recent call to action by a consortium of philanthropic organizations. With asthma a major contributor to childhood disease burden, studies of its spatial epidemiology can provide valuable insights into the emergence of health inequalities early in life.
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The relationship between non-communicable disease risk and mental wellbeing in adolescence: a cross-sectional study utilising objective measures in IndonesiaRisk factors for non-communicable diseases (NCDs, cardiovascular diseases, cancers, chronic respiratory diseases, diabetes, and mental disorders) arise in adolescence but are mostly framed as relevant to health in adulthood; little is known about the relationship between co-occurring NCD risks and mental wellbeing in young people.
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UV exposure and protection against allergic airways diseaseAsthma is a chronic inflammatory disease of the small and large conducting airway mucosa characterised by Th2 cell immunity.
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Toward improved prediction of risk for atopy and asthma among preschoolers: A prospective cohort studyAtopy and asthma are commonly initiated during early life, and there is increasing interest in the development of preventive treatments for at-risk children.
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Providing feedback on adherence increases use of preventive medication by asthmatic childrenThis study investigates the impact of measuring adherence and providing feedback on medication usage by children with unstable asthma.
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Regulatory role of IL10 genetic variations in determining allergen-induced TH2 cytokine responses in childrenInterleukin-10 is a key immunomodulatory cytokine the principal function of which is to limit the magnitude of immune response.
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Severity and persistence of asthma and mental health: a birth cohort studyThe goal of the current study was to investigate asthma and mental health among youth in the community.
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Do early-life viral infections cause asthma?Epidemiologic associations between viral lower respiratory infections (LRIs) and asthma in later childhood are well known