Bacteria persist within biofilms on the middle ear mucosa of children with recurrent and chronic otitis media however the mechanisms by which these...
Otitis media (OM) is a common disease in early childhood characterised by inflammation of the middle ear.
This study was the first to concurrently identify middle ear pathogens in both bacterial biofilm and intracellularly in the middle ear mucosa of chil…
We investigated the suggestion that otitis-prone children have an impaired antibody response in the context of pneumococcal vaccination.
Reviewed in this article these studies have identified positive association at 21 genes with association at five of these replicated in independent p…
Vaccines including conserved antigens from Streptococcus pneumoniae & nontypeable Haemophilus influenzae have the potential to reduce of otitis media.
We identified several novel candidate genes which warrant further analysis in cohorts matched more precisely for clinical phenotypes.
Both bacteria and viruses play a role in the development of acute otitis media, however, the importance of specific viruses is unclear.
Otitis media (OM) is a common childhood disease characterised by middle ear inflammation following infection
In Australia the 7-valent pneumococcal conjugate vaccine (PCV7) is administered at 2, 4 and 6 months of age, with no booster dose.