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Research
A comparison of major trauma patient transport destination in metropolitan Perth, Western AustraliaThis study examines the characteristics and outcomes of major trauma patients between transport destinations
Research
Associations of serum short-chain fatty acids with circulating immune cells and serum biomarkers in patients with multiple sclerosisAltered composition of gut bacteria and changes to the production of their bioactive metabolites, the short-chain fatty acids (SCFAs), have been implicated in the development of multiple sclerosis (MS). However, the immunomodulatory actions of SCFAs and intermediaries in their ability to influence MS pathogenesis are uncertain. In this study, levels of serum SCFAs were correlated with immune cell abundance and phenotype as well as with other relevant serum factors in blood samples taken at first presentation of Clinically Isolated Syndrome (CIS; an early form of MS) or MS and compared to healthy controls. There was a small but significant reduction in propionate levels in the serum of patients with CIS or MS compared with healthy controls.
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Associations of Early- and Later-Childhood Poverty with Child Cognitive Function in Indonesia: Effect Decomposition in the Presence of Exposure-Induced Mediator-Outcome ConfoundingOur analysis shows that early and late intervention to support household income have equal importance with regards to significance of impact.
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Initial acquisition and succession of the cystic fibrosis lung microbiome is associated with disease progression in infants and preschool childrenWe characterized the lower airways microbiome using BAL samples obtained from clinically stable CF young children who underwent bronchoscopy and chest CT.
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Early diet quality in a longitudinal study of Australian children: Associations with nutrition and body mass index later in childhood and adolescenceThe aims of this study were to determine whether early childhood dietary quality was associated with infant and adolescent nutrition, and body mass index.
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Essential fatty acids and mood: A systematic review of observational studiesEssential polyunsaturated (omega-3 and omega-6) fatty acids have been proposed to play a role in the aetiology of mood disorders. However, a systematic...
Research
Dahlem ConferenceThere is increasing evidence that the functional state of the immune system at birth is predictive of the kinetics of immune maturation in early infancy.
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Toll-like receptor 7 function is reduced in adolescents with asthmaAnti-viral innate immune responses may be impaired in asthma, although the mechanisms are not well understood.
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Prevention of neural tube defects with folateA programme of monitoring mandatory fortification has been established in Australia.
We are a collaborative group focused on improving outcomes for children with leukaemia. The Research Assistant will evaluate novel therapeutics in