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Research
Reduced socs1 expression in lung fibroblasts from patients with ipf is not mediated by promoter methylation or mir155The interleukin (IL)-6 family of cytokines and exaggerated signal transducer and activator of transcription (STAT)3 signaling is implicated in idiopathic pulmonary fibrosis (IPF) pathogenesis, but the mechanisms regulating STAT3 expression and function are unknown. Suppressor of cytokine signaling (SOCS)1 and SOCS3 block STAT3, and low SOCS1 levels have been reported in IPF fibroblasts and shown to facilitate collagen production. Fibroblasts and lung tissue from IPF patients and controls were used to examine the mechanisms underlying SOCS1 down-regulation in IPF.
Research
Assessing the unified airway hypothesis in children via transcriptional profiling of the airway epitheliumUpper and lower airways are conserved in their transcriptional composition, and variations associated with disease are present in both nasal and tracheal epithelium
Research
Tryptophan and arginine catabolic enzymes and regulatory cytokines in clinically isolated syndrome and multiple sclerosisHigher IDO and ARG expression in clinically isolated syndrome and multiple sclerosis provides one sustained homeostatic mechanism to control multiple sclerosis-associated inflammation
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Early mortality from external causes in Aboriginal mothers: A retrospective cohort studyWhilst a disproportionate number of Aboriginal women die from potentially preventable causes, no research has investigated mortality in Aboriginal mothers.
Research
Australasian Diabetes Data Network: Building a Collaborative ResourceA national collaboration was formed to provide longitudinal collection of T1D patient characteristics and outcomes, the Australasian Diabetes Data Network
Research
Early infant feeding and adiposity risk: from infancy to adulthoodIn our study, we aimed to examine early infant feeding and adiposity risk in a longitudinal cohort from birth to young adulthood using new as well as...
News & Events
Diabetes researcher Dr Aveni Haynes awarded prestigious international fellowshipCongratulations to Principal Research Fellow Dr Aveni Haynes from The Kids Research Institute Australia and the University of Western Australia.
News & Events
Hybrid Closed Loop insulin delivery system has potential to restore hypoglycaemia awarenessShort term use of a hybrid closed loop system might preferentially benefit people with type 1 diabetes who have impaired awareness of hypoglycaemia (IAH), according to new research from the Children's Diabetes Centre.
Research
Blueprint for the House Dust MiteThe completeness of the coverage of a genome assembly is a critical starting point for all genomic projects so considerable attention is given to the sequencing metrics, which showed high indicators of success.
Research
Evaluation of the Learning+ Pilot ProgramYasmin Adrienne Harman-Smith Gregory BA, BHlthSc(Hons), PhD BSocSci, MPhil Head, Early Years Systems Evidence; Head, Tenders Support Unit Project