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Research
Spatial analysis of hepatobiliary abnormalities in a population at high-risk of cholangiocarcinoma in ThailandCholangiocarcinoma (CCA) is a serious health challenge with low survival prognosis. The liver fluke, Opisthorchis viverrini, plays a role in the aetiology of CCA, through hepatobiliary abnormalities: liver mass (LM), bile duct dilation, and periductal fibrosis (PDF). A population-based CCA screening program, the Cholangiocarcinoma Screening and Care Program, operates in Northeast Thailand. Hepatobiliary abnormalities were identified through ultrasonography.
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Supporting Families ProjectProudly funded by a Telethon Trust Research Grant, the Supporting Families project started in 2024 with the aim of co-designing a new clinical pathway for children with early stage type 1 diabetes (T1D).
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A whole-of-population study of term and post-term gestational age at birth and children's developmentRelative risks of developmental vulnerability for each week of gestation were calculated with adjustment for confounders and addressing missing information.
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Exclusive breastfeeding increased by an internet interventionExclusive breastfeeding for 6 months is acknowledged universally as the optimal feeding method for infants in order to provide the greatest health and...
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Psychosocial moderators of associations between life events and changes in physical activity after leaving high schoolThis study examines the associations between life events & changes in leisure-time physical activity after leaving high school in young people from rural...
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Der p 11 is a major allergen for house dust mite-allergic patients suffering from atopic dermatitisHouse dust mites (HDMs) belong to the most potent indoor allergen sources worldwide and are associated with allergic manifestations in the respiratory tract.
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X-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genesSystematic sequencing of all X-chromosomal genes in patients with genetic evidence for X-chromosome locus involvement may resolve 58% of Fragile X-negative cases
Glycoprotein A as a biomarker of pulmonary infection and inflammation in children with cystic fibrosis Background: Serum Glycoprotein A (GlycA)
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Applying causal inference and Bayesian statistics to understanding vaccine safety signals using a simulation studyCommunity perception of vaccine safety influences vaccine uptake. Our objective was to assess current vaccine safety monitoring by examining factors that may influence the availability of post-vaccination survey data, and thereby the specificity and sensitivity of existing signal detection methods.
Research
Phage therapy could be key to conquering persistent bacterial lung infections in childrenPersistent bacterial lung infections in children lead to significant morbidity and mortality due to antibiotic resistance. In this paper, we describe how phage therapy has shown remarkable efficacy in preclinical and clinical studies, demonstrating significant therapeutic benefits through various administration routes.