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Ivacaftor or lumacaftor/ivacaftor treatment does not alter the core CF airway epithelial gene response to rhinovirus

We tested the hypothesis that treatment of CF epithelial cells with ivacaftor (Iva) or ivacaftor/lumacaftor (Iva/Lum) would improve control of rhinovirus infection.

Rhinovirus infection drives complex host airway molecular responses in children with cystic fibrosis

Rhinovirus infection drives complex host airway molecular responses in children with cystic fibrosis TEarly-life viral infections are responsible for

Structural determinants of long term functional outcomes in young children with cystic fibrosis

Structural determinants of long term functional outcomes in young children with cystic fibrosis BACKGROUND: Accelerated lung function decline in

Glycoprotein A as a biomarker of pulmonary infection and inflammation in children with cystic fibrosis

Glycoprotein A as a biomarker of pulmonary infection and inflammation in children with cystic fibrosis Background: Serum Glycoprotein A (GlycA)

Gene modifiers of cystic fibrosis lung disease: A systematic review

Gene modifiers of cystic fibrosis lung disease: A systematic review Background: Lung disease is the major source of morbidity and mortality in cystic

Regional differences in infection and structural lung disease in infants and young children with cystic fibrosis

This study aimed to explore the links between infection and where early damage due to CF is found in young children with CF. The results showed that