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A systematic review on the impact of delayed local therapy in patients with Ewing sarcoma of the pelvisLocal treatment of pelvic Ewing Sarcoma (EWS) is czhallenging due to complex anatomy and potential complications. Local therapy may be deferred to maintain chemotherapy dose-intensity, but the impact of this delay on outcomes remains unclear.
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Content Validation of the Communication Inventory Disability–Observer Reported CID-ORCDKL5 deficiency disorder is a rare and severe developmental and epileptic encephalopathy that has profound effects on communication. It is essential that communication be measured accurately for upcoming gene therapy trials. The Communication Inventory Disability-Observer Reported was developed from a framework of communication derived from parent/caregiver interview data in consultation with disability and communication experts, and after reviewing concepts in existing measures.
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Iron Deficiency in Young Australian Children: A Hidden Health Crisis Demanding Urgent ActionDesiree Silva MBBS, FRACP, MPH, PhD Co-Director, ORIGINS desiree.silva@thekids.org.au Co-Head, The ORIGINS Project Professor Desiree Silva is
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Oscillometry: clinical significance and applicationsRespiratory oscillometry (or the forced oscillation technique) is a highly practical lung function test that can be applied in a wide range of clinical scenarios in children and adults, including the clinic, intensive care unit, patient home monitoring and emergency departments. Oscillometry measurements complement spirometry in detecting abnormal lung function, measuring effects of treatment such as inhaled corticosteroids or bronchodilators, and changes due to disease activity.
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Predicting NSSI among trans young people: the role of transphobic experiences, body image, and gender dysphoriaNon-suicidal self-injury (NSSI) is particularly common among trans young people. NSSI is most commonly used as an emotion regulation strategy, which may explain the high prevalence of the behavior among trans young people, who often experience unique stressors. In the current study we test an application of the Pantheoretical Framework of Dehumanization, in which transphobic experiences, body surveillance, body dissatisfaction, and gender dysphoria are all theorized to predict NSSI.
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How immunity shapes the long-term dynamics of influenza H3N2Since its emergence in 1968, influenza A H3N2 has caused yearly epidemics in temperate regions. While infection confers immunity against antigenically similar strains, new antigenically distinct strains that evade existing immunity regularly emerge ('antigenic drift'). Immunity at the individual level is complex, depending on an individual's lifetime infection history.
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ESM-Q: A consensus-based quality assessment tool for experience sampling method itemsThe experience sampling method (ESM) is increasingly used by researchers from various disciplines to answer novel questions about individuals’ daily lives. Measurement best practices have long been overlooked in ESM research, and recent reviews show that item quality is often not reported in ESM studies. The absence of information about item quality may be partly explained by the lack of consensus on how ESM item quality should be evaluated.
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RSV: an update on prevention and managementRespiratory syncytial virus (RSV) is a common cause of respiratory tract infections in infants and young children, and adults over 60 years of age. Infants born prematurely, adults aged over 75 years, individuals with medical conditions such as chronic cardiac or respiratory disease, or obesity, and Aboriginal and Torres Strait Islander people are at increased risk of severe RSV disease.
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Renal Masses in Childhood: An Australian PerspectiveChildhood renal masses comprise a heterogeneous group of conditions that have a wide range of presentations. This review outlines an approach to the diagnostic work-up of childhood renal masses and discusses the most common presentations and treatments. Renal tumours make up 5% of childhood cancer in Australia, with Wilms tumour being the most common under age 10 years.
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Rural Exposure and Future Intent of Australian Dermatology TraineesCitation: Yap M, Weston S, McKinnon E, Sadler G. Rural Exposure and Future Intent of Australian Dermatology Trainees. Australas J Dermatol. 2025.