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Showing results for "early lung health"
Research
Primary Nasal Epithelial Cells as a Surrogate Cell Culture Model for Type-II Alveolar Cells to Study ABCA-3 DeficiencyATP Binding Cassette Subfamily A Member 3 (ABCA-3) is a lipid transporter protein highly expressed in type-II alveolar (AT-II) cells. Mutations in ABCA3 can result in severe respiratory disease in infants and children. To study ABCA-3 deficiency in vitro, primary AT-II cells would be the cell culture of choice although sample accessibility is limited. Our aim was to investigate the suitability of primary nasal epithelial cells, as a surrogate culture model for AT-II cells, to study ABCA-3 deficiency.
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Multiple-breath washout outcomes are sensitive to inflammation and infection in children with cystic fibrosisThe lung clearance index may be a useful surveillance tool for monitoring the presence and extent of lower airway inflammation and infection
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Lung function in African infants: A pilot studyUnsedated infant lung function measures of tidal breathing, MBW, and eNO are feasible in a semi-rural African setting
Cystic fibrosis (CF) is the most common life‐shortening genetic disease affecting children.
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PREDICT CF: Assessing the role of lung clearance index in predicting disease progression in children with cystic fibrosisThere is increasing evidence that the assessment of ventilation distribution using the multiple breath washout (MBW) technique is sensitive to changes in disease status of children with cystic fibrosis.
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Metabolomics to predict asthma in children (MAP Study)Childhood asthma begins as wheeze (a whistling sound produced by the airways during breathing) during preschool age.
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Chronic wet cough in Aboriginal children: It's not just a coughResults highlight the need for a culturally appropriate information and education of the importance of chronic wet cough in children
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The Global Lung Initiative 2012 reference values reflect contemporary Australasian spirometryWe aimed to ascertain the fit of the European Respiratory Society Global Lung Initiative 2012 reference ranges to contemporary Australasian spirometric data.
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Early life exposure to coal mine fire smoke emissions and altered lung function in young childrenInfant exposure to coal mine fire emissions could be associated with long-term impairment of lung reactance
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Normative multiple-breath washout data in school-aged children corrected for sensor errorGraham Kathryn Rachel Alana Hall Ramsey Foong Harper BAppSci PhD CRFS FANZSRS FThorSoc FERS BSc (Hons), PhD BSc (hons), PhD, MBiostat BSc (hons)