Search
News & Events
Vitamin B crucial to children’s mental healthA new study led by The Kids has uncovered a significant link between vitamin B levels and the mental health and wellbeing of children and adolescents.
News & Events
Empowering Aboriginal communities the key to suicide preventionA comprehensive research report into the high rates of suicide in the Kimberley has called for a major change
News & Events
NHMRC Fellowships awarded to support child health researchFour leading The Kids Research Institute Australia researchers have been awarded Fellowships from the National Health and Medical Research Council (NHMRC).
Research
Western Australian Child Development AtlasWe know that place, location, and geography can all influence health, wellbeing, and disease, and thus are important factors in policy development and service planning.
Research
Are women with major depression in pregnancy identifiable in population health data?Although record linkage of routinely collected health datasets is a valuable research resource, most datasets are established for administrative purposes and...
Research
Pre-pregnancy maternal overweight and obesity increase the risk for affective disorders in offspringMaternal pre-pregnancy obesity has been linked with an increased risk for negative emotionality and inattentiveness in offspring in early childhood.
One in three children in WA suffer iron deficiency leading to poor sleep, fussy eating, and behavioural difficulties. This project aims to develop mechanisms to prevent and treat the problems before they become clinically significant and translate findings to other communities to improve childhood wellness.
Research
Adolescent peer aggression and its association with mental health and substance use in an Australian cohortProspective longitudinal birth cohort data was used to examine the association between peer aggression at 14yrs and mental health and substance use at 17yrs...
Research
Assisted reproductive technology and birth defects: A systematic review and meta-analysisIt has been 10 years since we carried out a systematic search of the literature on birth defect risk in infants born following assisted reproductive...
Research
Early mental health morbidity and later smoking at 17 years of ageWe examined the relationship between the onset and pattern of childhood mental health disorders and subsequent current smoking status at age 17 years.
Research
Diagnosis and analysis of unexplained cases of childhood encephalitis in Australia using metatranscriptomic sequencingEncephalitis is most often caused by a variety of infectious agents identified through diagnostic tests utilizing cerebrospinal fluid. We investigated the clinical characteristics and potential aetiological agents of unexplained encephalitis through metagenomic sequencing of residual clinical samples from multiple tissue types and independent clinical review.
Research
Late-talking and risk for behavioral and emotional problems during childhood and adolescenceAlthough many toddlers with expressive vocabulary delay ("late talkers") present with age-appropriate language skills by the time they are of school age,...
Research
Minimal residual disease and outcome characteristics in infant KMT2A-germline acute lymphoblastic leukaemia treated on the Interfant-06 protocolThe outcome of infants with KMT2A-germline acute lymphoblastic leukaemia (ALL) is superior to that of infants with KMT2A-rearranged ALL but has been inferior to non-infant ALL patients. Here, we describe the outcome and prognostic factors for 167 infants with KMT2A-germline ALL enrolled in the Interfant-06 study.
Research
Neck/shoulder pain is more strongly related to depressed mood in adolescent girls than in boysA cross-sectional study of 1258, 14 year old girls and boys used self-report and physical examination measures to assess neck/shoulder pain in the last...
Research
Physical Activity-Related Practices and Psychosocial Factors of Childcare Educators: A Latent Profile AnalysisLimited research investigates early childhood education and care (ECEC) educators' involvement in promoting physical activity. The aim was to identify distinct profiles based on physical activity-related practices and psychosocial factors in ECEC educators and examine how they relate to the amount of time allocated to children's physical activity. A secondary analysis of educator-reported survey data from the Play Active study was undertaken.
Research
Stratification of Sepsis Patients on Admission into the Intensive Care Unit According to Differential Plasma Metabolic PhenotypesDelayed diagnosis of patients with sepsis or septic shock is associated with increased mortality and morbidity. UPLC-MS and NMR spectroscopy were used to measure panels of lipoproteins, lipids, biogenic amines, amino acids, and tryptophan pathway metabolites in blood plasma samples collected from 152 patients within 48 h of admission into the Intensive Care Unit (ICU) where 62 patients had no sepsis, 71 patients had sepsis, and 19 patients had septic shock.
Research
Ovulation induction and subfertile untreated conception groups offer improved options for interpreting risks associated with ARTTo identify and characterise appropriate comparison groups for population studies of health outcomes in ART-conceived births: ovulation induction (OI), subfertile untreated and fertile natural conceptions. Our secondary objective was to examine whether known risks of pregnancy complications and adverse birth outcomes in ART births are elevated in comparison with subfertile (untreated and OI) conception groups.
Research
Outcomes for Australian children with relapsed/refractory acute lymphoblastic leukaemia treated with blinatumomabWe report on the Australian experience of blinatumomab for treatment of 24 children with relapsed/refractory precursor B-cell acute lymphoblastic leukaemia (B-ALL) and high-risk genetics, resulting in a minimal residual disease (MRD) response rate of 58%, 2-year progression-free survival (PFS) of 39% and 2-year overall survival of 63%. In total, 83% (n = 20/24) proceeded to haematopoietic stem cell transplant, directly after blinatumomab (n = 12) or following additional salvage therapy (n = 8).