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Using acute tryptophan depletion to investigate predictors of treatment response in adolescents with major depressive disorder

The major hypothesis of this study is that acute tryptophan depletion will be negatively associated with mood and cognitive functioning

Nitrous oxide (N2O) and subsequent open-label SSRI treatment of adolescents with depression (NOTAD): Study protocol for a randomised controlled trial

The aim of this study is to investigate the antidepressant effects of N2O and N2O and SSRI combined.

The psychosocial burden of childhood overweight and obesity: evidence for persisting difficulties in boys and girls

Overweight and obese children reported greater psychosocial distress than healthy weight children, and these differences were more pronounced for girls than boys.

Cognitive performance in offspring of parents with severe mental illness: a meta-analysis

Parental severe mental illnesses (SMIs), including schizophrenia, bipolar disorder, and major depressive disorder (MDD), can impact children's well-being, yet existing meta-analyses are limited in scope and methodology and do not comprehensively assess cognitive and academic performance in offspring across SMIs.

Sex-based differences in long-term lipid metabolism, inflammation, and stress regulation after non-severe paediatric burns

Paediatric burn injuries are a global health concern with long-term health consequences, such as psychological, immune, and cardiovascular complications, that can persist even after non-severe injuries. Emerging evidence suggests that biological sex may influence post-burn outcomes in children, as female burn survivors have been shown to experience higher mortality, scarring, anxiety, depression, and poorer quality of life compared to males. 

“I don't really exist here”: A reflexive thematic analysis of dissociative symptoms described by adolescents and their parents and clinicians

Dissociative symptoms are associated with a range of negative outcomes, yet little is understood about how adolescents experience dissociation in their daily lives. This study aimed to describe adolescents’ dissociative symptoms from the perspective of adolescents, their parents, and their treating clinicians.

Depression and Anxiety Among Young Gender- and Sexuality-Diverse Adolescents

Gender- and sexuality-diverse (GSD) youths are at increased risk of depression and anxiety compared with their cisgender and heterosexual counterparts. Little is known about the risks for younger GSD adolescents (<15 years).

Exploring the evidence on housing and health among Indigenous peoples in high-income countries: A scoping review protocol

The objective of this scoping review is to understand the nature of the published evidence on housing suitability, affordability, insecurity, and homelessness in relation to physical and mental health, domestic violence, and health service use among Indigenous people in high-income countries.

“Society really does not like people with psychosis”: A thematic analysis of the stigma and self-stigma experiences of young people at-risk for psychosis

Stigma and self-stigma reduce self-esteem and increase hopelessness and suicidality. While psychotic disorders are widely recognized as the most stigmatizing of all mental health disorders, there is a dearth of research investigating how stigma and self-stigma are experienced by young people at ultra-high risk (UHR) for psychosis.

Harmonization of SDQ and ASEBA Phenotypes: Measurement Variance Across Cohorts

Harmonizing the scores obtained by different instruments that measure the same construct enable researchers to combine them in one analysis. An important step in harmonization is checking whether there is measurement invariance across populations.