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Showing results for "early lung health"
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Risk factors for poorer respiratory outcomes in adolescents and young adults born pretermThe respiratory outcomes for adult survivors of preterm birth in the postsurfactant era are wide-ranging with prognostic factors, especially those encountered after the neonatal period, poorly understood.
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Preschool Multiple-Breath Washout Testing. An Official American Thoracic Society Technical StatementConsensus recommendations are outlined to direct preschool device design, test performance, and data analysis for the MBW technique
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BEAT-CF: Bayesian Evidence-Adaptive Tool to optimise management of Cystic FibrosisAn innovative response-adaptive approach to driving improvements in health outcomes, applied to cystic fibrosis.
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Long-term medical and psychosocial outcomes in congenital diaphragmatic hernia survivorsSurvivors of CDH may have significant adverse long-term medical and psychosocial issues that would be better recognised and managed in a multidisciplinary clinic
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Progressive ventilation inhomogeneity in infants with cystic fibrosis after pulmonary infectionThis study aimed to determine how pulmonary inflammation & infection impacts on ventilation distribution throughout early life in people with cystic fibrosis.
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Primary Nasal Epithelial Cells as a Surrogate Cell Culture Model for Type-II Alveolar Cells to Study ABCA-3 DeficiencyATP Binding Cassette Subfamily A Member 3 (ABCA-3) is a lipid transporter protein highly expressed in type-II alveolar (AT-II) cells. Mutations in ABCA3 can result in severe respiratory disease in infants and children. To study ABCA-3 deficiency in vitro, primary AT-II cells would be the cell culture of choice although sample accessibility is limited. Our aim was to investigate the suitability of primary nasal epithelial cells, as a surrogate culture model for AT-II cells, to study ABCA-3 deficiency.
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Exhaled breath temperature in healthy children is influenced by room temperature and lung volumeExhaled breath temperature (EBT) has been proposed for the non-invasive assessment of airway inflammation
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Smoking during pregnancy, vitamin C supplementation, and infant respiratory healthThis article discusses the merits and potential shortcomings of a study reported previously showing that giving Vitamin C to women who smoked during...
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Key paediatric messages from AmsterdamKey messages from the abstracts presented at the European Respiratory Society International Congress
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Collecting exhaled breath condensate from non-ventilated preterm-born infants: a modified methodExhaled breath condensate (EBC) collection is a non-invasive, safe method for measurement of biomarkers in patients with lung disease. Other methods of obtaining samples from the lungs, such as bronchoalveolar lavage, are invasive and require anaesthesia/sedation in neonates and infants. EBC is particularly appealing for assessing biomarkers in preterm-born infants, a population at risk of ongoing lung disease.