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Showing results for "early lung health"

Research

Elevated leukotriene B4 and 8-isoprostane in exhaled breath condensate from preterm-born infants

Inflammation and oxidative stress play a key role in the development of bronchopulmonary dysplasia (BPD), possibly contributing to persistent respiratory morbidity after preterm birth. We aimed to assess if inflammatory markers were elevated in exhaled breath condensate (EBC) of infants born very prematurely (< 32 weeks gestation) at 12-16 corrected months of age, and if increased levels were associated with BPD diagnosis and respiratory morbidity.

Science at Home: Build a lung model!

Have you ever wondered how your lungs work? Researchers from our Children’s Lung Health Team show you how to make a simple lung model by using common household items.

Research

Pre-Post Intervention to Strengthen and Sustain the Paediatric ESCALATION System (The SPECS): Study Protocol

Promptly recognising changes in an acutely unwell child’s condition is fundamental to prevent tragic outcomes. Western Australian (WA) healthcare facilities used inconsistent and varied paediatric early warning systems. To improve care consistency, a standardised ESCALATION system, inclusive of family involvement and sepsis recognition, was developed.

Research

Chronic wet cough in Aboriginal children: It's not just a cough

Results highlight the need for a culturally appropriate information and education of the importance of chronic wet cough in children

Research

Research Note: Adaptive trials

This Research Note has explored the strengths, risks and potential complexity of adaptive trials

Research

The potential of antisense oligonucleotide therapies for inherited childhood lung diseases

Antisense oligonucleotides are an emerging therapeutic option to treat diseases with known genetic origin. In the age of personalised medicines, antisense oligonucleotides can sometimes be designed to target and bypass or overcome a patient's genetic mutation, in particular those lesions that compromise normal pre-mRNA processing. Antisense oligonucleotides can alter gene expression through a variety of mechanisms as determined by the chemistry and antisense oligomer design.

Cystic Fibrosis

Cystic fibrosis (CF) is the most common life‐shortening genetic disease affecting children.

Research

Consensus statement for inert gas washout measurement using multiple- and single- breath tests

Inert gas washout tests, performed using the single- or multiple-breath washout technique, were first described over 60 years ago.

Research

Metabolomics to predict asthma in children (MAP Study)

Childhood asthma begins as wheeze (a whistling sound produced by the airways during breathing) during pre­school age.

News & Events

Wal-yan researchers to join global respiratory congress in Vienna

Researchers from the Wal-yan Respiratory Research Centre are proud to be part of this prestigious event, contributing their expertise to the Congress' outstanding scientific programme.