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Showing results for "early lung health"
Have you ever wondered how your lungs work? Researchers from our Children’s Lung Health Team show you how to make a simple lung model by using common household items.
Research
The potential of antisense oligonucleotide therapies for inherited childhood lung diseasesAntisense oligonucleotides are an emerging therapeutic option to treat diseases with known genetic origin. In the age of personalised medicines, antisense oligonucleotides can sometimes be designed to target and bypass or overcome a patient's genetic mutation, in particular those lesions that compromise normal pre-mRNA processing. Antisense oligonucleotides can alter gene expression through a variety of mechanisms as determined by the chemistry and antisense oligomer design.
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Research Note: Adaptive trialsThis Research Note has explored the strengths, risks and potential complexity of adaptive trials
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Upper Airway Pathology Contributes to Respiratory Symptoms in Children Born Very PretermThe upper airway may play a role in the respiratory symptoms experienced by some very preterm children and should be considered by clinicians
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Consensus statement for inert gas washout measurement using multiple- and single- breath testsInert gas washout tests, performed using the single- or multiple-breath washout technique, were first described over 60 years ago.
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CF derived scoring systems do not fully describe the range of structural changes seen on CT scans in PCDStructural changes identified on CT scans in primary ciliary dyskinesia are not identical to those previously described in cystic fibrosis patients
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Increased exhaled nitric oxide in wind and brass musiciansPlaying a wind or brass (W/B) instrument is considered a strenuous activity for the respiratory system.
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Key paediatric messages from the 2016 European respiratory society international congressHighlight of some of the most interesting abstracts presented at the 2016 ERS International Congress, which was held in London
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Metabolomics to predict asthma in children (MAP Study)Childhood asthma begins as wheeze (a whistling sound produced by the airways during breathing) during preschool age.
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Humidified high-flow nasal cannula oxygen for bronchiolitis: Should we go with the flow?Current NICE 2015 guidelines for bronchiolitis state that the use of HFNC is becoming widespread without demonstration of additional efficacy.