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Research
A Diagnosis for All Rare Genetic Diseases: The Horizon and the Next FrontiersThere is a critical need for the field to develop and implement strategies to understand the mechanisms underlying all rare diseases and translate these to clinical care
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Survival and mortality in cerebral palsy: Observations to the sixth decade from a data linkage study of a total population register and National Death IndexSince 1990 mortality for those with severe cerebral palsy in Western Australia has tended to shift from childhood to early adulthood
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Early vaccination protects against childhood leukemia: A systematic review and meta-analysisGrowing evidence supports a role for infection in the etiology of ALL and the involvement of immune systems suggests that vaccination may also play a role.
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House dust allergy and immunotherapyHDM allergy is associated with asthma, allergic rhinitis and atopic dermatitis.
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Perinatal testosterone exposure and autistic-like traits in the general population: a longitudinal pregnancy-cohort studyIncreased prenatal testosterone exposure has been hypothesized as a mechanism underlying autism spectrum disorders (ASD).
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A subset of patients with systemic lupus erythematosus fails to degrade DNA from multiple clinically relevant sources.Patients with systemic lupus erythematosus (SLE) have a decreased ability to clear cell remnants and multiple deficiencies in the ability to degrade cellular...
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Timing of excision after a non-severe burn has a significant impact on the subsequent immune response in a murine modelEarly excision of the wound, during the phase of immune down-regulation initiated by the burn, maintains an innate and adaptive immune cell response
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A psychometric evaluation of the Connor–Davidson Resilience Scale for Australian Aboriginal youthThere is a paucity of quantitative measures of resilience specifically validated for young Aboriginal people in Australia. We undertook the first investigation of validity and reliability of the Connor-Davidson Resilience Scale in a sample of Australian Aboriginal people, with a focus on youth. We conducted a cross-sectional study of resilience among a sample of 122 Aboriginal youth (15–25 years old) in New South Wales and Western Australia, featuring self-completes of the 10-item CD-RISC in online (N = 22) and face-to-face (N = 100) settings.
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Feasibility and acceptability of the use of flash glucose monitoring encountered by Indigenous Australians with type 2 diabetes mellitus: initial experiences from a pilot studyType 2 diabetes mellitus (T2DM) is highly prevalent within the Indigenous Australian community. Novel glucose monitoring technology offers an accurate approach to glycaemic management, providing real-time information on glucose levels and trends. The acceptability and feasibilility of this technology in Indigenous Australians with T2DM has not been investigated.
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Impact of Body Composition on the Accuracy of a Medtronic Guardian Continuous Glucose Monitoring SystemContinuous glucose monitoring systems are used in therapeutic decisions for diabetes management, however, the impact of body composition on CGM accuracy is not known. Body composition variables were collected in an observational study designed to determine the accuracy of an investigational Medtronic Guardian™ sensor 3.