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Does machine learning have a role in the prediction of asthma in children?Asthma is the most common chronic lung disease in childhood. There has been a significant worldwide effort to develop tools/methods to identify children's risk for asthma as early as possible for preventative and early management strategies. Unfortunately, most childhood asthma prediction tools using conventional statistical models have modest accuracy, sensitivity, and positive predictive value.
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Variants associated with HHIP expression have sexdifferential effects on lung functionLung function is highly heritable and differs between the sexes throughout life. However, little is known about sexdifferential genetic effects on lung function. We aimed to conduct the first genome-wide genotype-by-sex interaction study on lung function to identify genetic effects that differ between males and females.
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The PELICAN (Prematurity's Effect on the Lungs In Children and Adults Network) ERS Clinical Research Collaboration: understanding the impact of preterm birth on lung health throughout lifeAn estimated 15 million babies (∼11%) are born preterm each year (before 37 weeks of gestation), the rates of which are increasing worldwide. Enhanced perinatal care, including antenatal corticosteroids, postnatal surfactant and improved respiratory management, have markedly improved survival outcomes since the 1990s, particularly for babies born very preterm (<32 weeks gestation). However, long-term pulmonary sequelae are frequent in preterm survivors and ongoing clinical management is often required.
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Pulmonary Gas Exchange Improves over the First Year in Preterm Infants with and without Bronchopulmonary DysplasiaRight shift of the peripheral oxyhaemoglobin saturation (SpO2) versus inspired oxygen pressure (PIO2) curve is a sensitive marker of pulmonary gas exchange. The aim of this study was to assess the impact of prematurity and bronchopulmonary dysplasia (BPD) on gas exchange and right-to-left shunt in the neonatal period, and its evolution over the first year of life.
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Standardization of Spirometry 2019 Update. An Official American Thoracic Society and European Respiratory Society Technical StatementStandards and consensus recommendations are presented for manufacturers, clinicians, operators, and researchers
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Preterm birth: Born too soon for the developing airway epitheliumThis review examines the consequences of preterm birth on the airway epithelium and explores the clinical relevance of currently available models
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The mask or the needle? Which induction should we go for?For children scheduled for elective surgery, intravenous induction has significant advantages with regards to reduced respiratory adverse events
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Respiratory function in healthy Emirati children using forced oscillationsForced oscillation technique measurements were feasible in Emirati school-children. New forced oscillation technique reference equation in Emirati children were derived.
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Surgical pleth index: Prediction of postoperative pain in children?It was the aim of this study to define a clinically appropriate SPI target to predict moderate-severe postoperative pain in children.
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The global lung function initiative (GLI) network: Bringing the world’s respiratory reference values togetherThe Global Lung Function Initiative (GLI) Network has become the largest resource for reference values for routine lung function testing ever assembled.