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A dramatic rise in food allergies over the past 20 years had Australian medical professionals scratching their heads, with three in every ten babies born each year developing food-related allergy or eczema.
Research
Interleukin-4 modulates type I interferon to augment antitumor immunityDespite advances in immunotherapy, metastatic melanoma remains a considerable therapeutic challenge due to the complexity of the tumor microenvironment. Intratumoral type I interferon (IFN-I) has long been associated with improved clinical outcomes. However, several IFN-I subtypes can also paradoxically promote tumor growth in some contexts.
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Incidence of cognitive errors in difficult airway management: an inference human factors study from the Pediatric Difficult Intubation RegistryCognitive errors are known contributors to poor decision-making in healthcare. However, their incidence and extent of their contribution to negative outcomes during difficult airway management are unknown. We aimed to identify cognitive errors during paediatric difficult airway management using data from the Pediatric Difficult Intubation (PeDI) registry, to determine patient and clinician factors associated with these errors, and their contribution to complications.
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National E-cigarette Monitoring and Evidence Consortium: Supporting informed research, policy and practice in AustraliaAlexander Larcombe BScEnv (Hons) PhD Honorary Research Fellow Honorary Research Fellow Associate Professor Alexander Larcombe began work at The Kids
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Strategies to Improve Research Participation By Older People With Cognitive Impairment: A Systematic ReviewOlder people with cognitive impairment are unrepresented in clinical research. Our objective was to review evidence for strategies to support their research inclusion and participation.
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Lifting the wellbeing of adolescents and young adults with type 1 diabetes: A feasibility study of the LIFT appAdolescents and young adults with type 1 diabetes have an increased risk of psychological distress. To address this, psychological support provided asynchronously via an app may be feasible. Our study aimed to explore feasibility and safety of the LIFT wellbeing app.

Between 1989 and 1991, almost 3,000 WA babies were recruited to the Raine Study - an ambitious research project which would yield a series of paradigm-shifting findings that changed scientific thinking. Three decades on, it has also changed the lives of those taking part.

The Yawardani Jan-ga Equine-Assisted Learning (EAL) research project, headed by Professor Juli Coffin in WA’s Kimberley region, is steadily growing its capacity to support the social, emotional and spiritual wellbeing of Aboriginal young people through the powerful medium of horses.
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Health behaviour change: Theories, progress, and recommendations for the next generation of physical activity researchAdaptive behaviour change is central to improving population health, yet poor adoption of health-enhancing behaviours contributes to noncommunicable diseases and so remains a global concern. Research on physical activity behaviour change has continued to expand and evolve since the turn of the millennium, guided by diverse theoretical approaches-from social cognitive theories, organismic dialectical approaches such as Self-Determination Theory, dual-process frameworks, and integrated practical models and taxonomies.
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Topical antibiotics for chronic suppurative otitis mediaChronic suppurative otitis media (CSOM), sometimes referred to as chronic otitis media, is a chronic inflammation and often polymicrobial infection (involving more than one micro-organism) of the middle ear and mastoid cavity, characterised by ear discharge (otorrhoea) through a perforated tympanic membrane. The predominant symptoms are ear discharge and hearing loss.