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Research
Copy number variation in tRNA isodecoder genes impairs mammalian development and balanced translationThe number of tRNA isodecoders has increased dramatically in mammals, but the specific molecular and physiological reasons for this expansion remain elusive. To address this fundamental question we used CRISPR editing to knockout the seven-membered phenylalanine tRNA gene family in mice, both individually and combinatorially.
Imagine living with a condition that requires you to make approximately 180 health- related decisions every day for the rest of your life.
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Perinatal testosterone exposure and autistic-like traits in the general population: a longitudinal pregnancy-cohort studyIncreased prenatal testosterone exposure has been hypothesized as a mechanism underlying autism spectrum disorders (ASD).
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House dust allergy and immunotherapyHDM allergy is associated with asthma, allergic rhinitis and atopic dermatitis.
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Epidemiology of hypoglycaemia in childhood-onset diabetes in Western AustraliaInvestigating the demographic, lifestyle and diabetes management factors associated with the incidence of severe hypoglycemia
News & Events
What’s in the air for AERIAL: ORIGINS Study publishes protocolORIGINS Study publishes protocol
Research
Early vaccination protects against childhood leukemia: A systematic review and meta-analysisGrowing evidence supports a role for infection in the etiology of ALL and the involvement of immune systems suggests that vaccination may also play a role.
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A Diagnosis for All Rare Genetic Diseases: The Horizon and the Next FrontiersThere is a critical need for the field to develop and implement strategies to understand the mechanisms underlying all rare diseases and translate these to clinical care
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Survival and mortality in cerebral palsy: Observations to the sixth decade from a data linkage study of a total population register and National Death IndexSince 1990 mortality for those with severe cerebral palsy in Western Australia has tended to shift from childhood to early adulthood
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Group a streptococcal carriage and seroepidemiology in children up to 10 years of age in Australia.This study aimed to acquire nationally representative epidemiological data on GAS in Australia to scope the appropriate age for vaccination with a potential...