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Healing Anthropocene Syndrome: Planetary Health Requires Remediation of the Toxic Post-Truth EnvironmentThe term “Anthropocene Syndrome” describes the wicked interrelated challenges of our time. We expand the discourse on positive social contagion and argue that empowerment through education can help lead to an information transformation with the aim of flourishing along every link in the person, place and planet continuum.
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Malt1 deficient mice develop osteoporosis independent of osteoclast-intrinsic effects of Malt1 deficiencyMalt1 deficient mice develop an osteoporotic phenotype with increased osteoclastogenesis in vivo, but suggest that this is caused by inflammation
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A global mathematical model of climatic suitability for Plasmodium falciparum malariaClimatic conditions are a key determinant of malaria transmission intensity, through their impacts on both the parasite and its mosquito vectors. Mathematical models relating climatic conditions to malaria transmission can be used to develop spatial maps of climatic suitability for malaria. These maps underpin efforts to quantify the distribution and burden of malaria in humans, enabling improved monitoring and control.
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Suppressing recurrence in Sonic Hedgehog subgroup medulloblastoma using the OLIG2 inhibitor CT-179OLIG2-expressing tumor stem cells have been shown to drive recurrence in Sonic Hedgehog (SHH)-subgroup medulloblastoma (MB) and patients urgently need specific therapies to target this tumor cell population.
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The genetic and epigenetic landscapes of the epithelium in asthmaGenetic factors in airway epithelial cells that are functionally associated with asthma pathogenesis
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Effectiveness of seasonal trivalent influenza vaccination against hospital-attended acute respiratory infections in pregnant womenInfluenza vaccination during pregnancy was associated with significantly fewer hospital attendances for ARI in pregnant women
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Hypermasculinised facial morphology in boys and girls with Autism Spectrum Disorder and its association with symptomatologyThis is the first study demonstrating facial hypermasculinisation in ASD and its relationship to social-communication difficulties in prepubescent children
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Comprehending the Health Informatics Spectrum: Grappling with System Entropy and Advancing Quality Clinical ResearchWe outline three scenarios from across the health spectrum where issues with health informatics are exemplified.
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Accumulation mode particles and LPS exposure induce TLR-4 dependent and independent inflammatory responses in the lungWe aimed to delineate the effects of LPS and AMP on airway inflammation, and potential contribution to airway disease by measuring airway inflammatory responses
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Sex differences in the association of phospholipids with components of the metabolic syndrome in young adultsThe aim of this study was to identify sex-specific differences in the metabolome and its relation to components of the metabolic syndrome in a young adult population