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Research

High-Rise Apartments and Urban Mental Health—Historical and Contemporary Views

High-rise apartment buildings have long been associated with the poor mental health of their residents

News & Events

State-first program to accelerate digital health in WA

A consortium of partners across the WA medical research sector will develop and deliver the State’s first digital health-specific program.

News & Events

Improving development and learning of children in Western Australia

Discover the EYI Research Profile at The Kids' Institute, showcasing innovative child health research and its impact on young lives.

News & Events

The Kids Research Institute Australia welcomes “top-up” funding for Medical Research Future Fund

Perth’s The Kids Research Institute Australia has welcomed a major funding boost for the Medical Research Future Fund (MRFF).

Research

Transplacental Innate Immune Training via Maternal Microbial Exposure: Role of XBP1-ERN1 Axis in Dendritic Cell Precursor Programming

We recently reported that offspring of mice treated during pregnancy with the microbial-derived immunomodulator OM-85 manifest striking resistance to allergic airways inflammation, and localized the potential treatment target to fetal conventional dendritic cell (cDC) progenitors. Here, we profile maternal OM-85 treatment-associated transcriptomic signatures in fetal bone marrow, and identify a series of immunometabolic pathways which provide essential metabolites for accelerated myelopoiesis.

Research

OPTIMUM study protocol: an adaptive randomised controlled trial of a mixed whole-cell/acellular pertussis vaccine schedule

Combination vaccines containing whole-cell pertussis antigens were phased out from the Australian national immunisation programme between 1997 and 1999 and replaced by the less reactogenic acellular pertussis (aP) antigens. In a large case-control study of Australian children born during the transition period, those with allergist diagnosed IgE-mediated food allergy were less likely to have received whole-cell vaccine in early infancy than matched population controls (OR: 0.77 (95% CI, 0.62 to 0.95)). We hypothesise that a single dose of whole-cell vaccine in early infancy is protective against IgE-mediated food allergy.

Research

Type 2 diabetes in children and adolescents across Australia and New Zealand: A 6‐year audit from The Australasian Diabetes Data Network (ADDN)

To assess the clinical and demographic characteristics of children and adolescents across Australia and New Zealand (NZ) with type 2 diabetes.

Research

A reduction in reported alcohol use in pregnancy in Australian Aboriginal communities: a prevention campaign showing promise

Glenn Martyn Pearson Symons BA (Education) PhD Candidate B.A. (Hons) PhD. Director of First Nations Strategy and Leadership; Head, First Nations

News & Events

The Kids welcomes new Closing the Gap targets

The Kids Research Institute Australia has welcomed the announcement of a new National Agreement on Closing the Gap.

News & Events

New Australia-first cyber safety app a guiding light for parents

Australian parents have a new weapon in the battle to keep their kids safe online with the launch of ‘Beacon’.