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Prevalence and Correlates of Observed Sun Protection Behaviors Across Different Public Outdoor Settings in Melbourne, AustraliaSkin cancer prevention efforts in Australia have increasingly incorporated a focus on protection during incidental sun exposure. This complements the long-present messages promoting protection in high-risk settings and avoidance of acute intense bouts of sun exposure.
Research
The pharmacokinetic properties of artemether and lumefantrine in Malaysian patients with Plasmodium knowlesi malariaThe aim of this study was to assess the pharmacokinetic properties of artemether, lumefantrine and their active metabolites in Plasmodium knowlesi malaria.
News & Events
Donna Cross joins the Telethon InstituteInternationally recognised child health researcher Professor Donna Cross will join The Kids for Child Health Research in 2014.
Research
Impact of Coronavirus Disease 2019 Public Health Measures on Detections of Influenza and Respiratory Syncytial Virus in Children During the 2020 Australian WinterPublic health measures targeting coronavirus disease 2019 have potential to impact transmission of other respiratory viruses. We found 98.0% and 99.4% reductions in respiratory syncytial virus and influenza detections, respectively, in Western Australian children through winter 2020 despite schools reopening. Border closures have likely been important in limiting external introductions.
Research
Does machine learning have a role in the prediction of asthma in children?Asthma is the most common chronic lung disease in childhood. There has been a significant worldwide effort to develop tools/methods to identify children's risk for asthma as early as possible for preventative and early management strategies. Unfortunately, most childhood asthma prediction tools using conventional statistical models have modest accuracy, sensitivity, and positive predictive value.
Research
Therapeutic targeting of the leukaemia microenvironmentIn recent decades, the conduct of uniform prospective clinical trials has led to improved remission rates and survival for patients with acute myeloid leukaemia and acute lymphoblastic leukaemia. However, high-risk patients continue to have inferior outcomes, where chemoresistance and relapse are common due to the survival mechanisms utilised by leukaemic cells.
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Gastro gap between Aboriginal and non-Aboriginal children shrinkingThe world's largest study of gastroenteritis trends in children has shown the disparity between Aboriginal and non-Aboriginal health may be improving.
Research
Bridging the gaps in test interpretation of SARS-CoV-2 through Bayesian network modellingIn the absence of an established gold standard, an understanding of the testing cycle from individual exposure to test outcome report is required to guide the correct interpretation of SARS-CoV-2 reverse transcriptase real-time polymerase chain reaction (RT-PCR) results and optimise the testing processes.
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Fiona Stanley appointed to Prime Minister's Science, Engineering and Innovation CouncilFiona Stanley appointed to Prime Minister's Science, Engineering and Innovation Council
Research
Stepwise maturation of the peptidyl transferase region of human mitoribosomesMitochondrial ribosomes are specialized for the synthesis of membrane proteins responsible for oxidative phosphorylation. Mammalian mitoribosomes have diverged considerably from the ancestral bacterial ribosomes and feature dramatically reduced ribosomal RNAs. The structural basis of the mammalian mitochondrial ribosome assembly is currently not well understood. Here we present eight distinct assembly intermediates of the human large mitoribosomal subunit involving seven assembly factors.
Research
The mitochondrial single-stranded DNA binding protein is essential for initiation of mtDNA replicationWe report a role for the mitochondrial single-stranded DNA binding protein (mtSSB) in regulating mitochondrial DNA (mtDNA) replication initiation in mammalian mitochondria. Transcription from the light-strand promoter (LSP) is required both for gene expression and for generating the RNA primers needed for initiation of mtDNA synthesis.
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New research links poor language to lack of Vitamin D in wombNew research has found that children of mums who had low levels of Vitamin D during pregnancy are twice as likely to have language difficulties.
Research
Longitudinal evidence of the impact of dog ownership and dog walking on mental healthEmerging evidence supports the physical health and social benefits of dog ownership. This study examined the longitudinal effect of dog ownership and dog walking on mental health.
News & Events
Building links for better researchWA's reputation as a research pioneer will be centre stage this week with a global gathering of health industry experts who share a passion for data
News & Events
WA leads world's largest study of language developmentWestern Australia will lead the largest, longest and most comprehensive study of language and literacy development in the world
News & Events
National funding success for child health researchersResearchers from the Telethon Institute have today been awarded $3.46 million in competitive grants and two early career fellowships from the NHMRC.
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A world first for Aussie kids putting Australia's children on the mapIn a world first, 96 per cent of communities in Australia now have vital information about their children's development
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Children and young people with CP needed for respiratory studyWest Australian study will look at the breathing and airway problems of children and with cerebral palsy (CP) to prevent serious respiratory problems
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How mums talk influences children’s perspective-taking abilityNew research shows that kids whose mums talk more frequently about others' thoughts tend to be better at taking another's perspective than other children.