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Research
Mapping the landscape of chromatin dynamics during naïve CD4+ T-cell activationT-cell activation induces context-specific gene expression programs that promote energy generation and biosynthesis, progression through the cell cycle and ultimately cell differentiation. The aim of this study was to apply the omni ATAC-seq method to characterize the landscape of chromatin changes induced by T-cell activation in mature naïve CD4+ T-cells.
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Sex differences in the association of phospholipids with components of the metabolic syndrome in young adultsThe aim of this study was to identify sex-specific differences in the metabolome and its relation to components of the metabolic syndrome in a young adult population
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Successful Treatment of Congenital Erythroleukemia With Low-Dose Cytosine ArabinosideWe report a term male with congenital acute erythroleukemia who achieved sustained remission with low-dose cytosine arabinoside alone
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Heat-mediated reduction of apoptosis in UVB-damaged keratinocytes in vitro and in human skin ex vivoUVB-induced p53-mediated cell cycle arrest and apoptosis are reduced in the presence of heat stress, leading to increased survival of DNA damaged cells
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Fetal alcohol spectrum disorders: Using knowledge, attitudes and practice of justice professionals to support their educational needsThere was widespread agreement of the need for more information and training about FASD to optimise outcomes for people with FASD engaging with justice system
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Differential gene network analysis for the identification of asthma-associated therapeutic targets in allergen-specific T-helper memory responsesDifferential network analysis of allergen-induced CD4 T cell responses can unmask covert disease-associated genes and pin point novel therapeutic targets
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Missing voices: Profile and extent of acquired communication disorders in Aboriginal and non-Aboriginal adult stroke survivors in Western AustraliaThe needs of Aboriginal stroke patients with acquired communication disorder should inform appropriate service design for speech pathology and rehabilitation
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Effectiveness of seasonal trivalent influenza vaccination against hospital-attended acute respiratory infections in pregnant womenInfluenza vaccination during pregnancy was associated with significantly fewer hospital attendances for ARI in pregnant women
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Development of a scale to evaluate midwives' beliefs about assessing alcohol use during pregnancyPrenatal alcohol exposure is an important modifiable cause of adverse fetal outcomes during and following pregnancy.
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The genetic and epigenetic landscapes of the epithelium in asthmaGenetic factors in airway epithelial cells that are functionally associated with asthma pathogenesis