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Unpacking the complex nature of the autism epidemicThis paper discusses changes in diagnostic criteria, decreasing age at diagnosis, improved case ascertainment, diagnostic substitution, and social influences.
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Increased longevity and the comorbidities associated with intellectual and developmental disabilityThe contributors, all world experts in their fields, also discuss what we can learn from the presence of co-morbidities.
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Airway narrowing assessed by anatomical optical coherence tomography in vitro: dynamic airway wall morphology and functionPrevious histological and imaging studies have shown the presence of variability in the degree of bronchoconstriction of airways sampled at different locations.
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Early immunological influences on asthma development: opportunities for early interventionEarly immunological influences on asthma development: opportunities for early intervention
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Hypoglycemia alarm enhancement using data fusionThe acceptance of closed-loop blood glucose (BG) control using continuous glucose monitoring systems (CGMS) is likely to improve.
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Effects of simulated tidal and deep breathing on immature airway contraction to acetylcholine and nerve stimulationIn adults, respiratory movements, such as tidal and deep breaths, reduce airway smooth muscle force and cause bronchodilation.
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Tumor eradication after cyclophosphamide depends on concurrent depletion of regulatory T cellsTumor cell death potentially engages with the immune system. However, the efficacy of anti-tumor chemotherapy may be limited by tumor-driven...
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Adult psychosocial outcomes of children with specific language impairment, pragmatic language impairment and autismEvidence that some children also develop autistic symptomatology over time has raised suggestions that developmental language disorder...
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The common BDNF polymorphism may be a modifier of disease severity in Rett syndromeRett syndrome (RTT) is caused by mutations in the transcriptional repressor methyl CpG-binding protein 2 (MECP2).
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Locally administered TLR7 agonists drive systemic antitumor immune responses that are enhanced by anti-CD40 immunotherapyTopical application of tumors with the TLR7 agonist imiquimod is an effective adjunct treatment for a range of primary dermatological cancers.