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Research

Developmental vitamin D deficiency increases foetal exposure to testosterone

Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders which are more common in males. The 'prenatal sex steroid' hypothesis links excessive sex-steroid exposure during foetal life with the behavioural differences observed in ASD. However, the reason why sex steroid exposure may be excessive remains unclear. Epidemiological studies have identified several environmental risk factors associated with ASD, including developmental vitamin D (DVD) deficiency.

Research

Association of suicidal behavior with exposure to suicide and suicide attempt: A systematic review and multilevel meta-analysis

prior exposure to suicide and prior exposure to suicide attempt in the general population are associated with increased odds of subsequent suicidal behavior

Research

RD-RAP: Beyond rare disease patient registries, devising a comprehensive data and analytic framework

We introduce and describe the concept of a Rare Disease Registry and Analytics Platform

Research

No detectable effects of acute tryptophan depletion on short-term immune system cytokine levels in healthy adults

The acute tryptophan depletion condition did not result in significant changes to cytokine concentrations for the entire study sample

Research

Primary prevention of severe lower respiratory illnesses in at-risk infants using the immunomodulator OM-85

The effects of OM-85 were strongest in the first winter season, with a trend for fewer children in the OM-85 group to have sLRIs and URIs

News & Events

Australia’s first DNA-based COVID-19 vaccine study set to begin at The Kids Research Institute Australia

Australia’s first needle-free, gene-based COVID-19 vaccine study will be spear-headed in WA by The Kids Research Institute Australia thanks to almost $6 million in Coronavirus Research Response funding announced by Health Minister Greg Hunt.

News & Events

The hidden burden of diabetes

When Jodie and Brad Scott welcomed their fourth child Heath into the world, they were prepared for the many sleepless nights that come with caring for newborns.

Research

Mental wellbeing in non-ambulant youth with neuromuscular disorders: What makes the difference?

Mental wellbeing was independently associated with academic achievement and perceived family support but not with physical health variables

Research

Prevalence of microcephaly in an Australian population-based birth defects register, 1980-2015

We identified a high proportion of cases without known cause, highlighting the need for clinicians to carefully investigate all possibilities, including emerging infections.

Research

Does alcohol outlet density differ by area-level disadvantage in metropolitan Perth?

This ecological study examines the distribution of liquor licences in Perth, Australia, and whether discrepancies in the distribution of retail land-uses could account for a socio-economic gradient.