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Research

Enablers and barriers to primary health care access for Indigenous adolescents: a systematic review and meta-aggregation of studies across Australia, Canada, New Zealand, and USA

Indigenous adolescents access primary health care services at lower rates, despite their greater health needs and experience of disadvantage. This systematic review identifies the enablers and barriers to primary health care access for Indigenous adolescents to inform service and policy improvements.

Research

Coupling of response biomarkers between tumor and peripheral blood in patients undergoing chemoimmunotherapy

Platinum-based chemotherapy in combination with anti-PD-L1 antibodies has shown promising results in mesothelioma. However, the immunological mechanisms underlying its efficacy are not well understood and there are no predictive biomarkers to guide treatment decisions.

Research

Does alcohol outlet density differ by area-level disadvantage in metropolitan Perth?

This ecological study examines the distribution of liquor licences in Perth, Australia, and whether discrepancies in the distribution of retail land-uses could account for a socio-economic gradient.

Research

Gestational age and school achievement: A population study

We examined gestational age from preterm to post-term against a national minimum standard for academic achievement in population data.

Research

Transcriptional landscape of Mycobacterium tuberculosis infection in macrophages

A comprehensive in depth gene expression/regulation profile in Mycobacterium tuberculosis-infected macrophages

Research

Macrolides in children with community-acquired pneumonia: Panacea or placebo?

Pneumonia, most often caused by a respiratory virus, is common in childhood.

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Primary prevention of severe lower respiratory illnesses in at-risk infants using the immunomodulator OM-85

The effects of OM-85 were strongest in the first winter season, with a trend for fewer children in the OM-85 group to have sLRIs and URIs

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RD-RAP: Beyond rare disease patient registries, devising a comprehensive data and analytic framework

We introduce and describe the concept of a Rare Disease Registry and Analytics Platform

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No detectable effects of acute tryptophan depletion on short-term immune system cytokine levels in healthy adults

The acute tryptophan depletion condition did not result in significant changes to cytokine concentrations for the entire study sample

Research

Mental wellbeing in non-ambulant youth with neuromuscular disorders: What makes the difference?

Mental wellbeing was independently associated with academic achievement and perceived family support but not with physical health variables