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Probiotic peanut oral immunotherapy versus oral immunotherapy and placebo in children with peanut allergy in Australia (PPOIT-003): a multicentre, randomised, phase 2b trialOral immunotherapy is effective at inducing desensitisation to allergens and induces sustained unresponsiveness (ie, clinical remission) in a subset of patients, but causes frequent reactions. We aimed to investigate whether addition of a probiotic adjuvant improved the efficacy or safety of peanut oral immunotherapy.
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Hot topics in paediatric immunology: IgE-mediated food allergy and allergic rhinitisThis article focuses on IgE-mediated food allergies and allergic rhinitis, the most commonly seen conditions in paediatric immunology.
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Nutritional Influences on Epigenetic Programming. Asthma, Allergy, and ObesityReliance on increasing use of dietary supplementation and fortification (eg, with folate) to compensate for increased consumption of processed foods is also...
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Does docosahexaenoic acid supplementation in term infants enhance neurocognitive functioning in infancy?The proposal that dietary docosahexaenoic acid (DHA) enhances neurocognitive functioning in term infants is controversial.
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The role of family and maternal factors in childhood obesityThe aim of this study was to investigate the relationship between a child's weight and a broad range of family and maternal factors.
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A Family's Journey at JHC: Analyses of routinely collected dataDesiree Silva MBBS, FRACP, MPH, PhD Co-Director, ORIGINS desiree.silva@thekids.org.au Co-Head, The ORIGINS Project Professor Desiree Silva is
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ADAPTS: Antibiotic Dysbiosis And Probiotics Trial in infantSDesiree Peter Silva Richmond MBBS, FRACP, MPH, PhD MBBS MRCP(UK) FRACP Co-Director, ORIGINS Head, Vaccine Trials Group desiree.silva@thekids.org.au
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Environmental and lifestyle changes in the antenatal population over the past three decades: A comparative study utilising Raine Study and Joondalup Health Campus birth cohort dataInvestigators: Catherine Nguyen, Lauren Fisher, Lauren Nguyen This study investigated changes in prevalence of environmental and lifestyle risk
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ORIGINS community wellbeing during the COVID-19 pandemicDesiree Dr Jackie Lisa Susan Silva Davis Gibson Prescott MBBS, FRACP, MPH, PhD BSc (Hons), PGradDipHlthProm, PhD BA (Hons), MPsych, PhD MBBS BMedSci
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Earth dreams: Reimagining ARPA for health of people, places and planetBold new approaches are urgently needed to overcome global health challenges. The proposed Advanced Research Projects Agency for Health (ARPA-H) is intended to provide rapid health breakthroughs.