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Bugging allergy; role of pre-, pro- and synbiotics in allergy preventionHere, we summarize and discuss findings of randomized clinical trials that have examined the effects of these strategies on short and long-term.
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Each meal matters in the exposome: Biological and community considerations in fast-food-socioeconomic associationsAs we discuss, equal weekly visits to major fast-food outlets by the affluent and deprived do not translate into biological equivalency.
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Validation of monoclonal anti-PKC isozyme antibodies for flow cytometry analyses in human T cell subsets and expression in cord blood T cellsWe have undertaken to validating the specificity of commercially available antibodies marketed for flow cytometry to measure PKCα, βI, βII, δ, ε, η, θ, ζ, ι/λ and μ
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Gut microbiome and innate immune response patterns in IgE-associated eczemaGut microbiome patterns have been associated with predisposition to eczema potentially through modulation of innate immune signalling.
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Maternal fish oil supplementation in pregnancy: a 12 year follow-up of a randomised controlled trial.We aimed to investigate the long-term effects (12 years) of fish oil supplementation in pregnancy on neurodevelopment, including cognition, language and fine...
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The maturation of immune functions in pregnancy and early childhoodThis book chapter explains the maturation of immune functions during pregnancy & in early childhood, and addresses the importance of early environmental...
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In “high-risk” infants with sufficient vitamin d status at birth, infant vitamin D supplementation had no effect on allergy outcomes: A randomized controlled trialEarly infancy oral vitamin D supplementation does not appear to reduce the development of early childhood allergic disease
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In-utero exposures and the evolving epidemiology of paediatric allergyThis paper discusses the rising prevalence of allergic disease in children. This review article considers recent findings in the field of paediatric immune...
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Vitality Revisited: The Evolving Concept of Flourishing and Its Relevance to Personal and Public HealthHuman flourishing, the state of optimal functioning and well-being across all aspects of an individual's life, has been a topic of philosophical and theological discussion for centuries. In the mid-20th century, social psychologists and health scientists began exploring the concept of flourishing in the context of health and high-level wellness.
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Gene dysregulation in acute HIV-1 infection – early transcriptomic analysis reveals the crucial biological functions affectedTranscriptomic analyses from early human immunodeficiency virus (HIV) infection have the potential to reveal how HIV causes widespread and lasting damage to biological functions, especially in the immune system. Previous studies have been limited by difficulties in obtaining early specimens.