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Research
Do children with autism 'switch off' to speech sounds? An investigation using event-related potentialsAutism is a disorder characterized by a core impairment in social behaviour. A prominent component of this social deficit is poor orienting to speech.
Mitochondrial diseases are devastating disorders for which there are no cures or effective treatments. Our project will focus on the prevention of mitochondrial diseases and discovery of effective cures.
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Coupling of response biomarkers between tumor and peripheral blood in patients undergoing chemoimmunotherapyPlatinum-based chemotherapy in combination with anti-PD-L1 antibodies has shown promising results in mesothelioma. However, the immunological mechanisms underlying its efficacy are not well understood and there are no predictive biomarkers to guide treatment decisions.
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Severe outcomes of malaria in children under time-varying exposureIn malaria epidemiology, interpolation frameworks based on available observations are critical for policy decisions and interpreting disease burden. Updating our understanding of the empirical evidence across different populations, settings, and timeframes is crucial to improving inference for supporting public health.
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Enablers and barriers to primary health care access for Indigenous adolescents: a systematic review and meta-aggregation of studies across Australia, Canada, New Zealand, and USAIndigenous adolescents access primary health care services at lower rates, despite their greater health needs and experience of disadvantage. This systematic review identifies the enablers and barriers to primary health care access for Indigenous adolescents to inform service and policy improvements.
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Mapping Drug-Resistant Tuberculosis Treatment Outcomes in Hunan Province, ChinaDrug-resistant tuberculosis (DR-TB) remains a major public health challenge in China, with varying treatment outcomes across different regions. Understanding the spatial distribution of DR-TB treatment outcomes is crucial for targeted interventions to improve treatment success in high-burden areas such as Hunan Province. This study aimed to map the spatial distribution of DR-TB treatment outcomes at a local level and identify sociodemographic and environmental factors associated with poor treatment outcomes in Hunan Province, China.
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Gestational age and school achievement: A population studyWe examined gestational age from preterm to post-term against a national minimum standard for academic achievement in population data.
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Macrolides in children with community-acquired pneumonia: Panacea or placebo?Pneumonia, most often caused by a respiratory virus, is common in childhood.
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RD-RAP: Beyond rare disease patient registries, devising a comprehensive data and analytic frameworkWe introduce and describe the concept of a Rare Disease Registry and Analytics Platform
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No detectable effects of acute tryptophan depletion on short-term immune system cytokine levels in healthy adultsThe acute tryptophan depletion condition did not result in significant changes to cytokine concentrations for the entire study sample