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High concentrations of middle ear antimicrobial peptides and proteins are associated with detection of middle ear pathogens in children with recurrent acute otitis mediaElevated antimicrobial proteins and peptides and cytokines in middle ear effusion are a marker of inflammation and bacterial persistence
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Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomicsWe identified the existence of more than 290 clinically associated genomic phylogroups across 22 countries, highlighting challenges in designing vaccines of global utility
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RD-RAP: Beyond rare disease patient registries, devising a comprehensive data and analytic frameworkWe introduce and describe the concept of a Rare Disease Registry and Analytics Platform
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Vitamin and mineral supplements: Gut health and probiotics: Probiotics for a healthy microbiome: An evidence-based approach to appropriate product choiceThis review discusses the available evidence base to help provide practical guidance when considering probiotics in practice
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No detectable effects of acute tryptophan depletion on short-term immune system cytokine levels in healthy adultsThe acute tryptophan depletion condition did not result in significant changes to cytokine concentrations for the entire study sample
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Community-based participatory action research on rheumatic heart disease in an Australian Aboriginal homeland: Evaluation of the ‘On track watch’ projectBased in 'both-way learning', the aim of this study was to co-design, implement and evaluate community-based participatory action research to achieve this vision
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Local Housing Characteristics Associated with Early Childhood Development Outcomes in Australian Disadvantaged CommunitiesAccess to safe, secure, and stable housing is a well-known social determinant of health
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Commissioning and performance characteristics of a pre-clinical image-guided radiotherapy systemCharacteristics of a small-animal radiotherapy device, the X-RAD SmART, are described following commissioning of the device for pre-clinical radiotherapy research
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Environmental and social determinants of acute rheumatic fever: a longitudinal cohort studyPrevention strategies in ARF endemic settings may be enhanced by targeting new members entering a community and children in environments of close contact
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The ORIGINS ProjectORIGINS is a new birth cohort study, collecting detailed information about the early environment's influence on a broad range of non-communicable diseases