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CCI-007, a novel small molecule with cytotoxic activity against infant leukemia with MLL rearrangements

Identified CCI-007 as a novel small molecule that displays rapid toxicity towards a subset of MLL-r, CALM-AF10 and SET-NUP214 leukemia cell lines

Improving epinephrine responses in hypoglycemia unawareness with real-time continuous glucose

The objective of this study was to determine whether real-time continuous glucose monitoring (CGM) with preset alarms at specific glucose levels would prove...

Effectiveness of a school-based mindfulness program for transdiagnostic prevention in young adolescents

Investigated mindfulness as a prevention program for anxiety, depression and eating disorders in early secondary school

Increased longevity and the comorbidities associated with intellectual and developmental disability

The contributors, all world experts in their fields, also discuss what we can learn from the presence of co-morbidities.

CD8α+ DCs are not the sole subset cross-presenting cell associated tumor antigens from a solid tumor

CD8α+ DCs are not the sole subset cross-presenting cell associated tumor antigens from a solid tumor

Trends in smoking rates by level of psychological distress-time series analysis of US national health interview survey data 1997-2014

People with mental health problems have high rates of smoking, and represent a large proportion of adult smokers in the United States.

Unpacking the complex nature of the autism epidemic

This paper discusses changes in diagnostic criteria, decreasing age at diagnosis, improved case ascertainment, diagnostic substitution, and social influences.

Adolescent bystanders' perspectives of aggression in the online versus school environments

Researchers' understanding of bystanders' perspectives in the cyber-environment fails to take young people's perceptions into account and remains imperfect.

Prenatal stress and risk of behavioral morbidity from age 2 to 14 years:

The maternal experience of stressful events during pregnancy has been associated with a number of adverse consequences for behavioral development offspring...

Psychotic experiences and their significance

Clinical perspective from the ultra high risk (UHR) paradigm, that aims to identify people at high risk of psychotic disorder