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The rates of RHD in Timor-Leste are among the highest in the world, and prevalence is higher among girls than boys
The authors present a variety of pressing clinical research questions on optimal RHD prevention and advanced care
Quantification of the disease burden caused by different risks informs prevention by providing an account of health loss different to that provided by a...
This review outlines a clinical development strategy detailing the phases of development required for registration of a candidate Group A streptococci vaccin
Rheumatic heart disease (RHD) after group A streptococcus (GAS) infections is heritable and prevalent in Indigenous populations. Molecular mimicry between human and GAS proteins triggers proinflammatory cardiac valve-reactive T cells.
We describe the initiation and summary outcomes of a public health system approach for complex undiagnosed patients- the Undiagnosed Diseases Program - WA
This review provides an update on the current status of Group A Streptococcus vaccine development, & describes global efforts to accelerate the development...
Echocardiographic screening for rheumatic heart disease (RHD) can identify individuals with subclinical disease who could benefit from antibiotic prophylaxis.
Total global disability-adjusted life-years remained largely unchanged from 1990 to 2015
A problem that applied researchers and practitioners often face is the fact that different institutions within research consortia use different scales to evaluate the same construct which makes comparison of the results and pooling challenging.