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Research

Wet Cough

A wet cough in a child for more than four weeks could indicate infection in the lungs. The wet cough is caused by mucus in the airway. The mucus becomes infected with bacteria and causes airway inflammation that can progress to permanent lung damage known as bronchiectasis.

Research

A multi-institutional retrospective pooled outcome analysis of molecularly annotated pediatric supratentorial ZFTA-fused ependymoma

ZFTA-RELA (formerly known as c11orf-RELA) fused supratentorial ependymoma has been recognized as a novel entity in the 2016 WHO classification of CNS tumors and further defined in the recent 2021 edition.

Research

The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial

BRAF genomic alterations are the most common oncogenic drivers in pediatric low-grade glioma.

Research

Flexible bronchoscopy insufflated and high-flow nasal oxygen pilot trial (BUFFALO protocol pilot trial)

Hypoxaemia occurs in approximately 30% of children during anaesthesia for flexible bronchoscopy. High-flow nasal oxygen (HFNO) can prolong safe apnoea time and be used in children with abnormal airways. During flexible bronchoscopy, there is limited evidence if HFNO confers advantages over current standard practice in avoiding hypoxaemia. The aim is to investigate feasibility of HFNO use during anaesthesia for flexible bronchoscopy to reduce frequency of rescue oxygenation and hypoxaemia. 

News & Events

Celebrating 35 years of impact at The Kids Research Institute Australia

Coinciding with the Institute’s 35th year of research to improve the health and wellbeing of children and families, the 2025 Impact Report celebrates research which has been translated into policy or practice, and which has led to a paradigm shift in the way we respond to childhood health and wellbeing.

Research

Molecular actions of Vitamin D in reproductive cell biology

The aim of this work is to review current metabolic and molecular aspects of the VitD-VitD receptor axis in reproductive medicine

Research

Systematic analysis of transcription start sites in avian development

CAGE in combination with single-molecule sequencing technology allows mapping of TSSs and genome-wide capture of promoter activities state cell populations.

Research

Premedication with salbutamol prior to surgery does not decrease the risk of perioperative respiratory adverse events in school-aged children

Premedication with salbutamol to children prior to their surgery did not reduce their risk of Perioperative respiratory adverse events

Research

Bipolar disorder in children and adolescents: diagnostic inpatient rates from 2000 to 2013 in Germany

The rate of Bipolar Disorder as a discharge diagnosis in German minors has increased significantly, consistently exceeding the general trend for a rise in rates for mental disorders

Research

Closed Loop Study - Multicentre

A Closed-Loop System will potentially have a major impact upon acute and chronic complications of diabetes as well as upon their quality of life