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Research

Resting Energy Expenditure and Metabolic Features in Children With Septo-Optic Dysplasia

Septo-optic dysplasia (SOD) is a major cause of congenital hypopituitarism and is known to be associated with overweight and obesity in up to 44% of children. Given the role of the hypothalamus in hormonal regulation, we sought to assess the association of resting energy expenditure (REE), appetite and physical activity with SOD. 

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PhD pathway program ensuring bright future for clinical research in WA

Two outstanding Perth Children’s Hospital clinicians will be supported to pursue a career in medical research, paving the way for more clinician-scientists in Western Australia.

Research

Clinical and demographic risk factors associated with mortality during early adulthood in a population-based cohort of childhood-onset Type 1 diabetes

This paper reports calculated standardized mortality ratios in patients with Type 1 diabetes, and assesses the association between poor management of...

Research

The challenges of developing and optimising an assay to measure 25-hydroxyvitamin D in saliva

We have developed an LC-MS/MS assay that accurately measures saliva 25(OH)D3 levels, which correlated with serum levels

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Effect of obesity on neonatal hypoglycaemia in mothers with gestational diabetes: A comparative study

To determine the influence of obesity on neonatal hypoglycaemia among infants born to gestational diabetes mellitus mothers.

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Prevention of Insulin-Induced Hypoglycemia in Type 1 Diabetes with Predictive Low Glucose Management System

The aim of this study was to determine whether predictive low glucose management (PLGM) system is effective in preventing insulin-induced hypoglycemia

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Regular peaks and troughs in the Australian incidence of childhood type 1 diabetes mellitus (2000–2011).

This study aimed to determine the incidence and incidence rate trends of type 1 diabetes mellitus in children aged 0–14 years...

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Glycaemic control of Type 1 diabetes in clinical practice early in the 21st century: An international comparison

Improving glycaemic control in people with Type 1 diabetes is known to reduce complications.

Research

Effect of antecedent moderate-intensity exercise on the glycemia-increasing effect of a 30-sec maximal sprint: a sex comparison

This study investigated whether a prior bout of moderate-intensity exercise attenuates the glycemia-increasing effect of a maximal 30-sec sprint.

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Real-world outcomes of insulin pump compared to injection therapy in a population-based sample of children with type 1 diabetes

Patients using insulin pump therapy had a better long-term glycemic control relative to the matched injection therapy cohort