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News & Events
Australia’s first DNA-based COVID-19 vaccine study set to begin at The Kids Research Institute AustraliaAustralia’s first needle-free, gene-based COVID-19 vaccine study will be spear-headed in WA by The Kids Research Institute Australia thanks to almost $6 million in Coronavirus Research Response funding announced by Health Minister Greg Hunt.
News & Events
The hidden burden of diabetesWhen Jodie and Brad Scott welcomed their fourth child Heath into the world, they were prepared for the many sleepless nights that come with caring for newborns.
The CMVictory Study aims to learn more about the safety and effectiveness of a potential CMV vaccine.
Contact us If you'd like to get in touch, please contact us by phone or email. Phone: 0400 450 240 Email: vtg@thekids.org.au PAEDS Paediatric Active
Understanding how families engage with screen technologies and how it may influence child development
This project aims to investigate the impact of a non-severe burn injury on children's health for life.
Virtual Scientific Launch Day: Wednesday 1 December 2021 (Australia) Time: 7am Australian WST/ 10am Australian EDST / 12pm NZ DST North America:
News & Events
Gifted pump proves a life changer for familyOliver Bowman is too young to understand the enormity of having type 1 diabetes but his young parents Brooke and Aidan know all too well the reality of having a child with a chronic disease.
Research
Small-molecule screen reveals synergy of cell cycle checkpoint kinase inhibitors with DNA-damaging chemotherapies in medulloblastomaMedulloblastoma (MB) consists of four core molecular subgroups with distinct clinical features and prognoses. Treatment consists of surgery, followed by radiotherapy and cytotoxic chemotherapy. Despite this intensive approach, outcome remains dismal for patients with certain subtypes of MB, namely, MYC-amplified Group 3 and TP53-mutated SHH. Using high-throughput assays, six human MB cell lines were screened against a library of 3208 unique compounds. We identified 45 effective compounds from the screen and found that cell cycle checkpoint kinase (CHK1/2) inhibition synergistically enhanced the cytotoxic activity of clinically used chemotherapeutics cyclophosphamide, cisplatin, and gemcitabine.
Research
Improving lung health of Aboriginal children hospitalised with chest infections – Aboriginal Children’s Excellent (ACE) Lung Health StudyThe ACE project is led by Dr Pamela Laird and aims to improve post-hospitalisation follow-up of Indigenous children hospitalised with acute lower respiratory tract infections.