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Technology powering researchResearchers at The Kids are harnessing the power of apps and other online tools to ensure the results of their research reach those who need it most – children, young people and families.
Research
Immune checkpoint therapy responders display early clonal expansion of tumor infiltrating lymphocytesImmune checkpoint therapy (ICT) causes durable tumour responses in a subgroup of patients, but it is not well known how T cell receptor beta (TCRβ) repertoire dynamics contribute to the therapeutic response.
Research
Topical antiseptics for chronic suppurative otitis mediaThe effectiveness and safety profile of antiseptics in the treatment of chronic suppurative otitis media is uncertain
Research
Clinical outcomes for young people with screening-detected and clinically-diagnosed rheumatic heart disease in FijiYoung people with screening-detected RHD have worse health outcomes than screen-negative cases in Fiji.
Research
Fetal head circumference growth in children with specific language impairmentThe aim was to characterise fetal brain growth in children with specific language impairment (SLI). A nested case-control study was set in Perth, WA.
Research
#TraumaTok-TikTok Videos Relating to Trauma: Content AnalysisExperiencing a traumatic event can significantly impact mental and emotional well-being. Social media platforms offer spaces for sharing stories, seeking support, and accessing psychoeducation. TikTok (ByteDance), a rapidly growing social media platform, is increasingly used for advice, validation, and information, although the content of this requires further study.
Research
Tonsils at Telethon: developing a standardised collection of tonsil photographs for group A streptococcal (GAS) researchGroup A streptococcus (GAS) infections, such as pharyngitis and impetigo, can lead to rheumatic fever and rheumatic heart disease (RHD). Australian Aboriginal and Torres Strait Islander populations experience high rates of RHD and GAS skin infection, yet rates of GAS pharyngitis are unclear.
ORIGINS has several sub-projects exploring allergy development within the cohort, with a focus on nutritional strategies for allergy prevention.
Research
Colostrum as a Protective Factor Against Peanut Allergy: Evidence From a Birth CohortFood allergy affects families' quality of life, can be lifelong and life-threatening, urging the identification of early modifiable risk factors. Formula feeding in the first days of life may increase the risk of cow's milk allergy, a risk often attributed to cow's milk allergens exposure. Early formula feeding also reduces the colostrum intake, the first 3 days' milk, which is rich in bioactive compounds critical for immune and gut health. This study investigates whether partial colostrum feeding increases the risk of food allergy beyond cow's milk.
Find answers to frequently asked questions about ORIGINS.