Search
Research
Anaphylaxis triggered by benzyl benzoate in a preparation of depot testosterone undecanoateWe report the first case of an anaphylactic reaction to Reandron 1000 (depot testosterone undecanoate with a castor oil and benzyl benzoate vehicle).
Research
Neurocognitive Outcomes in Young Adults With Early-Onset Type 1 DiabetesThe aim of this study was to reexamine the neurocognitive function of a cohort of young adults with early-onset type 1 diabetes and compare their cognitive...
Research
Lower cardiorespiratory fitness in children with Type 1 diabetesThe present study aimed to compare cardiorespiratory fitness levels in children with and without Type 1 diabetes.
Research
Perinatal risk factors for childhood Type 1 diabetes in Western Australia - a population-based study (1980-2002)To investigate perinatal risk factors for childhood Type 1 diabetes in Western Australia, using a complete population-based cohort.
Research
A Database of the Complications of Obesity in ChildrenThe Obesity Database records the characteristics and medical complications of children with obesity who present to treatment at Princess Margaret Hospital
Research
Glycemic and Psychosocial Outcomes of Advanced Hybrid Closed-Loop Therapy in Youth With High HbA1c: A Randomized Clinical TrialTo determine the efficacy of advanced hybrid closed-loop therapy in a high-risk cohort of youth on continuous subcutaneous insulin infusion with or without continuous glucose monitoring with suboptimal glycemia.
Research
Protocol for the Australian Type 1 Diabetes National Screening Pilot: Assessing the feasibility and acceptability of three general population screening models in childrenOne third of Australian children diagnosed with type 1 diabetes present with life-threatening diabetic ketoacidosis (DKA) at diagnosis. Screening for early-stage, presymptomatic type 1 diabetes, with ongoing follow-up, can substantially reduce this risk (<5% risk). Several screening models are being trialled internationally, without consensus on the optimal approach. This pilot study aims to assess three models for a routine, population-wide screening programme in Australia.
Research
A microRNA-based dynamic risk score for type 1 diabetesIdentifying individuals at high risk of type 1 diabetes (T1D) is crucial as disease-delaying medications are available. Here we report a microRNA (miRNA)-based dynamic (responsive to the environment) risk score developed using multicenter, multiethnic and multicountry ('multicontext') cohorts for T1D risk stratification. Discovery (wet and dry lab) analysis identified 50 miRNAs associated with functional β cell loss, which is a hallmark of T1D.
Research
Maternal body mass index, gestational weight gain, and the risk of overweight and obesity across childhood: An individual participant data meta-analysisHigher maternal pre-pregnancy BMI and gestational weight gain were associated with an increased risk of childhood overweight/obesity
Research
Pre-and Postnatal Vitamin D Status and Allergy Outcomes in Early ChildhoodThe dramatic increase in the prevalence of allergic disease in recent decades reflects environmental and behavioural changes that have altered patterns of early immune development. The very early onset of allergic diseases points to the specific vulnerability of the developing immune system to environmental changes and the development of primary intervention strategies is crucial to address this unparalleled burden.