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Research

Evaluating the Extent of Clinical Uncertainty Among Treatment Options for Patients with Early-Onset Scoliosis

The objective of this study was to evaluate areas of clinical uncertainty among pediatric spine surgeons regarding the treatment of early-onset scoliosis.

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Maternal life stress events in pregnancy link to children's school achievement at age 10 years

Maternal antenatal exposure to life stress events has differing effects on the school performance of male and female offspring.

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Exposure to UV Wavelengths in Sunlight Suppresses Immunity. To What Extent is UV-induced Vitamin D3 the Mediator Responsible?

In experimental models, both vitamin D3-dependent and vitamin D3-independent pathways have been implicated in the mechanisms of UVR-induced systemic...

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Fetal growth and childhood acute lymphoblastic leukemia: Findings from the childhood leukemia international consortium

The evidence that accelerated fetal growth is associated with a modest increased risk of childhood ALL is strong and consistent with known biological...

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Maternal pre-pregnancy body mass index and internalizing and externalizing problems in offspring

Exposure to elevated maternal pre-pregnancy BMI is associated with increased levels of internalizing and externalizing problems throughout childhood and...

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Parental occupational exposure to engine exhausts and childhood brain tumors

Increased risks were observed for maternal exposure to diesel exhaust any time before the child's birth and paternal exposure around the time of the child's...

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Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: A systematic analysis

Measuring disease and injury burden in populations requires a composite metric that captures both premature mortality and the prevalence and severity of...

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Early development and regression in Rett syndrome

Our findings provide additional insight into the early clinical profile of Rett syndrome.

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Swimming pools in remote Aboriginal communities

Providing remote communities with access to chlorinated swimming pools has been considered as a possible strategy for reducing ear and skin infection rates...

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Functioning and post-school transition outcomes for young people with Down syndrome

Our analysis shows that functioning in activities of daily living was related to post-school day occupation. Current health status and behaviour were found...