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Research
Using record linkage to examine testing patterns for respiratory viruses among children born in Western AustraliaUsing linked data, we describe changes in respiratory virus testing among children born in Western Australia in 1996-2012
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Vitamin D over the first decade and susceptibility to childhood allergy and asthmaWe aimed to research relationships between 25(OH)D levels from birth to 10 y/o and susceptibility to allergic sensitization, respiratory issues and asthma.
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World Allergy Organization-McMaster University Guidelines for Allergic Disease Prevention (GLAD-P): PrebioticsDevelop evidence-based recommendations about the use of prebiotics in the prevention of allergy
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Influence of maternal obesity on the long-term health of offspringIncluding immediate implications for pregnancy complications, increasing evidence implicates maternal obesity having a major impact on long term child health.
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Patterns of multiple risk exposures for low receptive vocabulary growth 4-8 years in the Longitudinal Study of Australian ChildrenOur results demonstrate a range of multiple risk profiles in a population-representative sample of Australian children and highlight the mix of risk factors faced by children
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Self-harm: Prevalence estimates from the second Australian Child and Adolescent Survey of Mental Health and WellbeingThe demonstrated higher risks in young people for continued harm or possible death support the need for ongoing initiatives to reduce self-harm
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‘Black Out Rage Gallon’ (aka borg): An investigation of a risky drinking trend on TikTokA 'Black Out Rage Gallon' (borg) is a customised, individual alcoholic beverage popularised on TikTok, whereby half the water in a gallon jug is replaced with alcohol (usually spirits), flavourings, electrolytes and caffeine. We investigated the characteristics and portrayal of the emerging alcohol trend associated with the hashtag descriptor #borg on TikTok.
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Gene editing and cardiac disease modelling for the interpretation of genetic variants of uncertain significance in congenital heart diseaseGenomic sequencing in congenital heart disease (CHD) patients often discovers novel genetic variants, which are classified as variants of uncertain significance (VUS). Functional analysis of each VUS is required in specialised laboratories, to determine whether the VUS is disease causative or not, leading to lengthy diagnostic delays.
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Maternal diet during breastfeeding: Could it influence food allergy risk in children?Human milk is rich in immuno-modulatory factors that have the potential to shape immune development and influence allergy risk in children. In this article, we describe how breast milk may contribute to making the infant less prone to developing allergies.
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Functional characterization of the MED12 p.Arg1138Trp variant in females: implications for neural development and disease mechanismSeven female individuals with multiple congenital anomalies, developmental delay and/or intellectual disability have been found to have a genetic variant of uncertain significance in the mediator complex subunit 12 gene. The functional consequence of this genetic variant in disease is undetermined, and insight into disease mechanism is required.