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We identify, develop and commercialise the technologies and innovations developed by our scientists and clinicians.

News & Events

Western Australia has been highly successful at containing community spread of COVID-19 to date.

News & Events

Have you ever wondered how other parents manage their kids’ device use? As part of a survey for our Cyber Savvy Project, The Kids researchers asked a group of parents for their top tips regarding their child's use of devices.

News & Events

The D-Light program, set up in 2014, aims to shed light on the amount of sun exposure that will promote good health in children and adolescents.

News & Events

A new study of child maltreatment over the last 20 years in developed countries has found no consistent decrease in rates despite a raft of policy initiatives.

Research

Medulloblastoma (MB) consists of four core molecular subgroups with distinct clinical features and prognoses. Treatment consists of surgery, followed by radiotherapy and cytotoxic chemotherapy. Despite this intensive approach, outcome remains dismal for patients with certain subtypes of MB, namely, MYC-amplified Group 3 and TP53-mutated SHH. Using high-throughput assays, six human MB cell lines were screened against a library of 3208 unique compounds. We identified 45 effective compounds from the screen and found that cell cycle checkpoint kinase (CHK1/2) inhibition synergistically enhanced the cytotoxic activity of clinically used chemotherapeutics cyclophosphamide, cisplatin, and gemcitabine.

We aim to discover and develop safer and more effective treatments by doing inventive and rigorous research to improve outcomes for kids with cancer.

Research

We are uncertain about the effectiveness of topical antibiotics in improving resolution of ear discharge in patients with chronic suppurative otitis media

Research

Describe the epidemiology of Staphylococcus aureus bacteremia in children and adolescents younger than 18 years from Australia and New Zealand

News & Events

It’s time to back off from the fear-mongering around severe hypoglycaemia, according to Children's Diabetes Centre researchers who point to increasing evidence that improved glycaemic control in children with type 1 diabetes is not associated with increasing rates of hypoglycaemia.