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Research
Early life predictors of obstructive sleep apnoea in young adults: Insights from a longitudinal community cohort (Raine study)Obstructive sleep apnea (OSA) increases the risk of perioperative adverse events in children. While polysomnography (PSG) remains the reference standard for OSA diagnosis, oximetry is a valuable screening tool. The traditional practice is the manual analysis of desaturation clusters derived from a tabletop device using the McGill oximetry score. However, automated analysis of wearable oximetry data can be an alternative. This study investigated the accuracy of wrist-worn oximetry with automated analysis as a preoperative OSA screening tool.
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Patterns of multiple risk exposures for low receptive vocabulary growth 4-8 years in the Longitudinal Study of Australian ChildrenOur results demonstrate a range of multiple risk profiles in a population-representative sample of Australian children and highlight the mix of risk factors faced by children
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The Influence of Grandparents on Children’s Dietary Health: A Narrative ReviewTo examine and synthesise recent evidence on the role of grandparents in shaping children's dietary health.
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Self-harm: Prevalence estimates from the second Australian Child and Adolescent Survey of Mental Health and WellbeingThe demonstrated higher risks in young people for continued harm or possible death support the need for ongoing initiatives to reduce self-harm
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BAL Inflammatory Markers Can Predict Pulmonary Exacerbations in Children With Cystic FibrosisPulmonary exacerbations in cystic fibrosis are characterized by airway inflammation and may cause irreversible lung damage. Early identification of such exacerbations may facilitate early initiation of treatment, thereby potentially reducing long-term morbidity. Research question: Is it possible to predict pulmonary exacerbations in children with cystic fibrosis, using inflammatory markers obtained from BAL fluid?
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World Allergy Organization-McMaster University Guidelines for Allergic Disease Prevention (GLAD-P): PrebioticsDevelop evidence-based recommendations about the use of prebiotics in the prevention of allergy
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Associations Among Early Stimulation, Stunting, and Child Development in Four Countries in the East Asia–PacificThis study examined associations among preschool attendance, home learning activities, stunting status, and early child development using data from the validation study of the East Asia–Pacific Early Child Development Scales (EAP-ECDS).
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Comparing the effects of sun exposure and vitamin D supplementation on vitamin D insufficiency, and immune and cardio-metabolic functionAdults living in the sunny Australian climate are at high risk of skin cancer, but vitamin D deficiency (defined here as a serum 25-hydroxyvitamin D...
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The influence of the early childhood education and care environment on young children’s physical activityThe PLAYCE Study instruments provide reliable measures of early childhood education and care physical activity environments
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Does late childbearing increase the risk for behavioural problems in children? A longitudinal cohort studyThis study aimed to examine the relationship between advanced parental age and behavioural outcomes in offspring in a longitudinal cohort of children in...
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"The problem with running"-Comparing the propulsion strategy of children with Developmental Coordination Disorder and typically developing childrenThis study compared strategies of propulsion and power generation at the ankle during late stance/early swing in both walking and running in children with...
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Changes in the clinical and epidemiological features of group A streptococcal bacteraemia in Australia's northern territoryWe aimed to measure the incidence and severity of invasive Group A Strep disease in the NT since 1996.
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A Genome-Wide Search for Type 2 Diabetes Susceptibility Genes in an Extended Arab FamilyWe performed a discovery GWAS in an extended UAE family (N = 178; 66 diabetic; 112 healthy) genotyped on the Illumina Human 660 Quad Beadchip, with...
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Setting the RECORD straight: Developing a guideline for the reporting of studies conducted using observational routinely collected dataThere has been a dramatic increase in the availability of "routine data" for research purposes, including data from electronic medical records,...
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Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunityTo gain further insight into the genetic architecture of psoriasis, we conducted a meta-analysis of 3 genome-wide association studies (GWAS) and 2...