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Research
Maternal prenatal stress exposure and sex-specific risk of severe infection in offspringMaternal stressful life events during pregnancy have been associated with immune dysregulation and increased risk for asthma and atopy in offspring. Few studies have investigated whether prenatal stress is associated with increased overall or specific infectious diseases in childhood, nor explored sex differences. We sought to examine the relationship between the nature and timing of maternal stress in pregnancy and hospitalisation with infection in offspring.
An outline of ORIGINS sub-projects by name
News & Events
Triage phone serviceA reminder we have updated our Phone Triage System and provided a triage helpful tips sheet for all families to access.
News & Events
Developing a pencil graspIn this blog, Senior Occupational Therapist Gayle Hillen explores the steps to developing a functional pencil grasp.
News & Events
Looking at autism through a social modelIn​ this blog, Speech Pathologist Linda Arabi discusses the social model and how it influences the supports we provide to autistic children and their families.
News & Events
Embrace Big Idea 2023 winners announcedPhoto (clockwise from top-left): Dr Craig Taplin, Mx Rigel Paciente, Ms Heather Roby, Dr Keely Bebbington, Dr Alix Woolard.
ORIGINS has several sub-projects exploring allergy development within the cohort, with a focus on nutritional strategies for allergy prevention.
Research
Colostrum as a Protective Factor Against Peanut Allergy: Evidence From a Birth CohortFood allergy affects families' quality of life, can be lifelong and life-threatening, urging the identification of early modifiable risk factors. Formula feeding in the first days of life may increase the risk of cow's milk allergy, a risk often attributed to cow's milk allergens exposure. Early formula feeding also reduces the colostrum intake, the first 3 days' milk, which is rich in bioactive compounds critical for immune and gut health. This study investigates whether partial colostrum feeding increases the risk of food allergy beyond cow's milk.
Research
Genome-wide association study of intraocular pressure identifies the GLCCI1/ICA1 region as a glaucoma susceptibility locusWe found a novel association between intraocular pressure and a common variant at 7p21 near to GLCCI1 and ICA1.
Research
Adolescent peer aggression and its association with mental health and substance use in an Australian cohortProspective longitudinal birth cohort data was used to examine the association between peer aggression at 14yrs and mental health and substance use at 17yrs...