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Research

The diagnostic odyssey to Rett syndrome: The experience of an Australian family

The diagnosis of a rare disorder is dependent on the clinician's particular knowledge and experience, and can be challenging when the presentation is variable.

News & Events

Researchers to focus on MS inflammation puzzle

The Kids Research Institute Australia researchers will seek to better understand the relationship between antibodies and inflammation in people with multiple sclerosis (MS), thanks to a generous grant from MS Research Australia.

News & Events

Crucial advancement in the treatment of childhood sarcoma

Cure Cancer and The Kids Research Institute Australia researcher Dr Ben Wylie announced new potential treatment in time for Childhood Sarcoma Awareness month.

News & Events

The Kids infectious diseases researcher named a WA Young Tall Poppy

A The Kids researcher focused on ensuring kids are protected from infectious diseases will be named among WA’s most outstanding young scientists at the upcoming 2021 Young Tall Poppy Science Awards.

News & Events

Ideas Grants to support innovative research

Two research teams, led by The Kids Research Institute Australia, have been awarded more than $2 million to fund innovative projects.

Research

Timing and temporal trends of influenza and pertussis vaccinations during pregnancy in three Australian jurisdictions: The Links2HealthierBubs population-based linked cohort study, 2012–2017

Antenatal inactivated influenza and pertussis-containing vaccines offer protection against severe respiratory infections for pregnant women and infants <6 months of age. Both vaccines are recommended in pregnancy; however, little is known about temporal or jurisdictional trends and predictors of uptake.

Research

Walking the walk to include pregnant participants in non-obstetric clinical trials: Insights from the SNAP Trial

Despite several calls for greater inclusion of pregnant people in non-obstetric clinical trials, their systematic exclusion remains common practice. Excluding pregnant individuals from clinical trials may result in unintended consequences such as inadequate treatment of medical conditions in pregnancy, inappropriate dosing of medications, and investigational therapies being used off-label outside of the context of a clinical trial, risking adverse events in the absence of demonstrated efficacy.

STARS for Kids

Strengths-based, tiered, accessible, resources and supports (STARS) for Kids for parent, carers and their children.

Research

Novel method to select meaningful outcomes for evaluation in clinical trials

A standardised framework for selecting outcomes for evaluation in trials has been proposed by the Core Outcome Measures in Effectiveness Trials working group. However, this method does not specify how to ensure that the outcomes that are selected are causally related to the disease and the health intervention being studied. Causal network diagrams may help researchers identify outcomes that are both clinically meaningful and likely to be causally dependent on the intervention, and endpoints that are, in turn, causally dependent on those outcomes.

Research

Raising strong, solid Koolunga: Values and beliefs about early child development among Perth's Aboriginal community

We detail the unique findings from an Aboriginal early child development research project with a specific focus on the Nyoongar/Aboriginal community of Perth