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Defective function at the epithelial junction: A novel therapeutic frontier in asthma?

The airway epithelium forms a highly regulated physical barrier that normally prevents invasion of inhaled pathogens and allergens from the airway lumen.

Interaction between adaptive and innate immune pathways in the pathogenesis of atopic asthma: Operation of a lung/bone marrow axis

Atopic asthma is the most common form of asthma, particularly during childhood, and in many cases it persists into adult life.

Vitamin D and atopy and asthma phenotypes in children: a longitudinal cohort study

Vitamin D has been linked in some studies with atopy- and asthma-associated phenotypes in children with established disease,but its role in disease inception...

Two newly identified cat allergens: The von Ebner gland protein Fel d 7 and the latherin-like protein Fel d 8

Characterization of the complete IgE binding spectrum of cat allergens is important for the development of improved diagnosis and effective immunotherapeutics.

Regulatory role of IL10 genetic variations in determining allergen-induced TH2 cytokine responses in children

Interleukin-10 is a key immunomodulatory cytokine the principal function of which is to limit the magnitude of immune response.

Association between human rhinovirus C and severity of acute asthma in children

A new and potentially more pathogenic group of human rhinovirus (HRV), group C (HRVC), has recently been discovered.

My child is wheezing – what should I do?

Almost 50 per cent of preschool children will experience at least one episode of wheeze, a whistling sound produced by the airways during breathing.

Can a simple urine test predict asthma? New study aims to find out

The Kids Research Institute Australia researchers are investigating whether a simple urine test could predict whether young children with wheezing symptoms will go on to develop asthma.

Very preterm babies at risk of declining lung function throughout childhood

A The Kids Research Institute Australia study published in The Lancet Child & Adolescent Health has found that survivors of very preterm birth face declining lung function