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Prenatal alcohol exposure is associated with a range of adverse offspring neurodevelopmental outcomes. Several studies suggest that PAE modifies DNA methylation in offspring cells and tissues, providing evidence for a potential mechanistic link to Fetal Alcohol Spectrum Disorder.

When examining the association between prenatal alcohol exposure and fetal effects, the timing and intensity of exposure have been ignored in epidemiological st

Data linkage of population administrative data is being investigated as a tool for pharmacovigilance in pregnancy in Australia.

The goal was to examine the associations between dose, pattern, and timing of prenatal alcohol exposure (PAE) and birth defects.

Alcohol exposure in pregnancy is a common and modifiable risk factor for poor pregnancy and child outcomes.

To establish baseline prevalence of neural tube defects (NTDs) prior to mandatory folic acid fortification in Australia.

Rates of Down syndrome (DS) show considerable international variation, but a systematic assessment of this variation is lacking.

The aim of this study was to examine trends of Down syndrome (DS) in relation to maternal age and termination of pregnancies (ToP) in 20 registries

There is a lack of evidence regarding the effect of dose, pattern and timing of prenatal alcohol exposure and behaviour problems in children aged 2 years.

This study describes the impact of having a sibling with Down syndrome or Rett syndrome using a questionnaire completed by parents.