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Background: We assessed the effect of posture on ventilation distribution and the impact on associations with structural lung disease.
Mosaic attenuation on expiratory chest computed tomography (CT) is common in early life cystic fibrosis (CF) and often referred to as "air trapping"
This is the largest collection of normative T LCO data, and the first global reference values available for T LCO.
The lung clearance index may be a useful surveillance tool for monitoring the presence and extent of lower airway inflammation and infection
To obtain comprehensive data on lung structure and function in mid-childhood from survivors of preterm birth.
This review summarizes what we have learned about early lung disease in children with CF and discusses the implications for clinical practice and research
We aimed to quantify the diagnostic utility of mannitol challenge testing for asthma in a community cohort and a symptomatic wheezing subset of this cohort.
To assess the determinants of early lung function in African infants.
The significance of both indoor and outdoor sources of air pollution and effect modifiers such as green space and heating require further investigation
Survivors of preterm birth (<37 weeks' gestation) have low peak oxygen uptake, a global measure of aerobic fitness and an established predictor of increased morbidity and mortality. However, little is known about other cardiopulmonary outcome measures in this population. We addressed the hypothesis that preterm birth is associated with abnormal respiratory, cardiovascular and metabolic responses to exercise, as assessed by cardiopulmonary exercise testing, via a systematic review and meta-analysis.