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Research

High risk of early sub-therapeutic penicillin concentrations after intramuscular benzathine penicillin G injections in Ethiopian children and adults with rheumatic heart disease

Intramuscular benzathine penicillin G (BPG) injections are a cornerstone of secondary prophylaxis to prevent acute rheumatic fever (ARF) and rheumatic heart disease (RHD). Uncertainties regarding inter-ethnic and preparation variability, and target exposure profiles of BPG injection are key knowledge gaps for RHD control.

Research

Spatiotemporal patterns of tuberculosis in Hunan province, China

Tuberculosis (TB) is the leading cause of death from a bacterial pathogen worldwide. China has the third highest TB burden in the world, with a high reported burden in Hunan Province (amongst others). This study aimed to investigate the spatial distribution of TB and identify socioeconomic, demographic, and environmental drivers in Hunan Province, China. Numbers of reported cases of TB were obtained from the Tuberculosis Control Institute of Hunan Province, China.

Research

Improving Influenza Vaccination in Children With Comorbidities: A Systematic Review

Children with medical comorbidities are at greater risk for severe influenza and poorer clinical outcomes. Despite recommendations and funding, influenza vaccine coverage remains inadequate in these children. We aimed to systematically review literature assessing interventions targeting influenza vaccine coverage in children with comorbidities and assess the impact on influenza vaccine coverage.

Research

Optimising a 6-plex tetanus-diphtheria-pertussis fluorescent bead-based immunoassay

Small volume assays are required for large-scale research studies and in particular paediatric trials, where multiple measures are required from a single sample. Fluorescent bead-based technology (Bioplex/Luminex) allows high through-put and simultaneous quantification of multiple analytes in a single test. This technology uses sets of microspheres, each with a unique spectral address that can be coated with a different antigen of interest.

News & Events

Six-minute Strep A tests dramatically cut wait time in remote settings

Children at risk of potentially life-threatening Strep A infections no longer have to wait five days for timely treatment, thanks to a The Kids Research Institute Australia study conducted in the remote Kimberley region of Western Australia.

News & Events

Latest infectious disease guidelines aim to keep childcare ‘bug-free’

The National Health and Medical Research Council (NHMRC) has launched their sixth edition of Staying healthy: Preventing infectious diseases in early childhood education and care services in a bid to tackle the transmission of germs amongst young kids.

News & Events

Why should all primary school aged kids get a free flu vaccine this winter?

With COVID-19 being a major issue this year, is it still important to have a flu vaccine? And why have school aged children been included for a free vaccine?

News & Events

Pioneering technique opens new window on first week of life

An international team of researchers has pioneered a technique which gives unprecedented insight into the dramatic changes occurring in a baby’s body in the first week of life.

News & Events

New national guideline set to tackle skin infections

When health organisations in the north-west of WA requested urgent action to address the region’s high rate of skin infections, Dr Asha Bowen answered the call.

News & Events

The Kids skin researcher awarded prestigious L’Oréal-UNESCO Women in Science fellowship

Dr Asha Bowen, Head of Skin Health at the Wesfarmers Centre of Vaccines and Infectious Diseases, has been awarded a 2018 Fellowship as part of the prestigious L’Oréal-UNESCO Women in Science program.