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Research

Effects of human rhinovirus on epithelial barrier integrity and function in children with asthma

This study demonstrates novel intrinsic differences in tight junctions gene and protein expression between airway epithelial cells of children with and without asthma

Research

Interferon regulatory factor 7 is a major hub connecting interferon-mediated responses in virus-induced asthma exacerbations in vivo

The objective of this study was to elucidate the molecular networks that underpin virus-induced exacerbations in asthmatic children in vivo.

Research

Interferon regulatory factor 7 is a major hub connecting interferon-mediated responses in virus-induced asthma exacerbations in vivo

The objective of this study was to elucidate the molecular networks that underpin virus-induced exacerbations in asthmatic children in vivo.

Research

Molecular characterization of Der p 10: A diagnostic marker for broad sensitization in house dust mite allergy

Tropomyosins represent clinically relevant seafood allergens but the role of mite tropomyosin

Research

CD4 allergen tetramers

The introduction of class II tetramers for identifying antigen-binding CD41 cells has lagged behind the use of class I tetramers because of difficulties...

Research

Influence of secular trends and sample size on reference equations for lung function tests

The aim of our study was to determine the contribution of secular trends and sample size to lung function reference equations, and establish the number...

Research

Many Healthy Lungs

In partnership with Derbarl Yerrigan Health Service and the Broome Regional Aboriginal Medical Service, we aim to improve Aboriginal lung health by determining for the first time the baseline lung function of Aboriginal Australians.

Research

Mechanisms of Acute Viral Respiratory Illness in Children (MAVRIC)

Large numbers of children need emergency medical treatment each year for respiratory illnesses, particularly for wheezing and asthma.

Research

Immunodominant T-cell epitopes in the VP1 capsid protein of rhinovirus species A and C

Our results indicate a dissociation between the antibody and T-cell responses to rhinoviruses